Protein Overview: vab-10

General Information:
Name(s) found:	vab-10 / CE35150 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006876 locus:vab-10 status:Confirmed UniProt:G5EEC4 protein_id:CAD90186.2 [WormBase] gi\|71997197\|ref\|NP_001021853.1\| Variable ABnormal morphology family member (vab-10) [Caenorhabditis elegans] [NCBI NR] gi\|33300865\|emb\|CAD90175.2\| C. elegans protein ZK1151.1a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|33300471\|emb\|CAD90186.2\| C. elegans protein ZK1151.1a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|27763987\|emb\|CAD44323.1\| VAB-10A protein [Caenorhabditis elegans] [NCBI NR] [wormpep111.fasta] Hypothetical protein ZK1151.1a [Caenorhabditis elegans]gi\|33300865\|emb\|CAD90175.2\| Hypothetical protein ZK1151.1a [Caenorhabditis elegans]gi\|27763987\|emb\|CAD44323.1\| VAB-10A protein [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] CE35150 WBGene00006876 locus:vab-10 status:Confirmed TR:O18290 protein_id:CAD90186.2 [wormpep150.fasta] 35150 WBGene00006876 locus:vab-10 status:Confirmed TR:O18290 protein_id:CAD90186.2 [wormpep130-phg-ecoli-orf-rand.fasta] locus:vab-10 status:Confirmed TN:CAD90186 protein_id:CAD90186.2 [wormpep115.fasta.reversed] CE35150 WBGene00006876 locus:vab-10 status:Confirmed UniProt:O18290_CAEEL protein_id:CAD90186.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE35150 WBGene00006876 locus:vab-10 status:Confirmed UniProt:O18290_CAEEL protein_id:CAD90186.2\| [wormORF-contam.fasta] Hypothetical protein ZK1151.1a [Caenorhabditis elegans] [nr-271106-contam.fasta] VAB-10A protein [Caenorhabditis elegans] [nr-271106-contam.fasta] Variable ABnormal morphology family member (vab-10) [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE35150 WBGene00006876 locus:vab-10 status:Confirmed UniProt:O18290 protein_id:CAD90186.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] CE35150 WBGene00006876 locus:vab-10 status:Confirmed UniProt:G5EEC4 protein_id:CAD90186.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] Isoform of G5EDD3, Uncharacterized protein OS=Caenorhabditis elegans GN=vab-10 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	3436 amino acids
Gene Ontology:
Cellular Component:	intracellular organelle [IDA] basal plasma membrane [IDA] membrane [IEA] intermediate filament [IDA] apical plasma membrane [IDA] proteinaceous extracellular matrix [IEA]
Biological Process:	cell cycle arrest [IEA] DNA repair [IEA] hermaphrodite genitalia development [IMP] signal transduction [IEA] locomotion [IMP ] embryonic development ending in birth or egg hatching [IMP ] post-embryonic body morphogenesis [IMP ] positive regulation of growth rate [IMP] protein amino acid dephosphorylation [IEA] cell adhesion [IEA] gamete generation [IMP] blood coagulation [IEA] reproduction [IMP] growth [IMP] chemotaxis [IEA] locomotory behavior [IMP ] nematode larval development [IMP ] morphogenesis of an epithelium [IMP] gastrulation with mouth forming first [IMP]
Molecular Function:	actin binding [IEA] protein tyrosine phosphatase activity [IEA] calcium ion binding [IEA] signal transducer activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGERYRSHH AVDPSDAQEK EVLDHYELNR EKYNDERDNV QKKTFTKWVN KHLSKTDHKI  60
   61 DDLFVDLRDG YALIALLEAL TGERIQKENG YTRFHRIQNV QYCLDFLKKK NIKLVNIRPE 120
  121 DIVEGNGKLT LGLIWTIILN FQVSVIRQRL LLESSQHEQM SAKHTTTNSQ VSLHGSDATS 180
  181 ARDALLQWAR RVTAGYPRVN VNNFSSSWRD GLAFNAILHR YRSSAIDWNK ISSDSVSNTE 240
  241 RLNNAFAAAD REFGVERLLD AEDVDTNNPD EKSIITYVSS LYNALPHEPE MSRLQKVQEE 300
  301 YIEEAYEWRE WVVRAIQLVD DRHLQGTASE LIYELQRFRE DDLPPREEQK RRLTLVYEHL 360
  361 EKVMRSTELF AIPHELSAPE LQRVWNELQN SIDRRFDVLE RHRIQEGNSN DLLSRLARGI 420
  421 GITNEKLDLI LKRIEDVEAR VDTSPPAAVE RTVSEIVDDL NALESPIARF FEDVEELKSM 480
  481 QHPEANDFYK QVYGLHQRRT TYLDRLTNQI LVRLGVRTDS LHKENQQRLE NMRKTSFSRV 540
  541 EECIEWVRVR MEKLTTMEFL EDLETLEHVF EQHKFDNRDI QDFRQNVDEC IARQAEVSAE 600
  601 DTYEYCELLR VLESEYQQLR DLSAGRMLDL DSLIAFVRAA QLELIWVSER ESIEVTRNWS 660
  661 DIKQLDLPML TNYYKQLLHE MELREKQYND VHNQGAALLN QGHPAIRVIE VYLRQMQSQW 720
  721 DWLLALSKCL EEHLRDALNL KSFMEEASDA EAWIQEQSVR LENNYNRTDF SLEEGERFLR 780
  781 ELDEIKEILN KYHQVLMALT ERCASISPLW QRGERIPHPI KVTALCDYSD ENVTIKAGDD 840
  841 VYLLDNSDLI KWTIRDISGA EGQVPSVVFR IPPTDARLTA LLNRLLQQFE KLKKLWDKKH 900
  901 RMVRFNMVLN TMRTIQGWDL DTFNSIDPDQ RDAIMKALND DANKLLSELD PNDPLALRLR 960
  961 EELRRTNEHF WNLLNASQKP PEPDWASQYD QKMAELLKKL EEAWRELNDA VGKPISRSPE1020
 1021 DLERVIHAHK RFEDALQALD SDVANVKELF RQLPNPTPTQ RVNHDRLNGL WDDLWDLSRM1080
 1081 YVERIKVLES VLNGMVEVAD IVRQHEITLN SFDDLPAALD KLRGHHSQLL EINMVLKVSK1140
 1141 LGAQNEHFSQ QQTVIDQLNR NVALLRQHVS RTRINEGHHP DVDAIEDEVQ KLNVRWENVN1200
 1201 SQIASRLLAV ESALQIQMVY RSEYETEMSW LDTVEETINR LRKPEELRPE QYQQQLDMLI1260
 1261 AEYTNLQEHT QAIEHVNKEG GRFIHEAKIF DAKLGQYSDG IVGIHGPGIK SEFRRTKPQP1320
 1321 KNGSQIVTEE LELLNRRFAQ LSSLILERRN TMQVLIQNWK RQKQEEEDRR RAEEEEKRRA1380
 1381 FEAARLKALE DAERLRRERE DAEARRRAKD DADRARRMAE DAERARREAE EAERRRREEE1440
 1441 ERRRREAEDR KRRQDEEDRR RREEEERRRR EEEEKRRKKP DFDLKIQKPT MNIEPVVTSA1500
 1501 GDEWEIVDPI GDRAKISEVE DEMQTFAEET ITNTQFYEME GNLNKKTGEV LTFIEAIRQG1560
 1561 NLTAAGQFFD IPSASVMSLE EAAKYGLVEQ DLPTVLNTTW GIHHPETRQP ITLSEAIRIG1620
 1621 LYDSNIRQFR DIHTGEILSQ SDLMSKGIAN WETVLKLIKE KIMKLPPTSL ANALEKRMVD1680
 1681 PQTGVFKGRT TDMELQLWAA IYHGYLSIEN PEHVTTIGTS LTDAIENGFI NANNAEFNDR1740
 1741 NSNDSFKLRD AVSKRTGLIN NDVVEIVQMT DDEKKRVPLG AALVRNVIGV KDGKYTNLAS1800
 1801 RQSMSLKEAH QDGLIGKALT LEEAAQNKLV DSSGYFVDRG ILGQRYTLLE AIVAGLIDAE1860
 1861 VRHIVDPNEN DVISISEAME RGLLLPNGKI VLEKDEKEFT IPEAVHEGLL TKRVRHSIFN1920
 1921 IRGIRNTETS QNLSFNEAVE AGVIIPNAER VVDLQTQESF LITDDRAKNL IEVALHELLT1980
 1981 TPVGIKNDRG AYELNLVRAV SSGIIDPVKG VFFNKNTKHE LSTKEAYEQG FITLRGALKV2040
 2041 FGLLNVPPAL VTPAKKLDRT RRIGRPGQEG GADGNHVTVT LQDAMRQGLV GNQRYVHGKV2100
 2101 DLSLEEALNR GLLDPNSQWI MPDQSKGDGP TIEEKTTETM TETGQQLAPK YFPDKNIEES2160
 2161 VTTVKRVRTT ETTALGGPGG VSVYRSIAGG KGALEVPSRG YHIYEAERKG LIDLTNGKIS2220
 2221 APNVDRVLSF AEGIELGIID ATTIQVSTGG RSVSVKEALE KKIMESDGSV NGRNIEQAVE2280
 2281 AKTIVIDAEP LVPYNNQSKN IIQIPSGNGP IISFRQVGQP VVEESTQSWE FDTQQGVFVD2340
 2341 NLTGEKLSLE RALATGKVAP EDISVRDGLT GREMPLEEAE KWGIIDSKNR YYFDKSQNKR2400
 2401 MSYTEAAQQH LMYLTGGVPE NASDAVHTTV KVQTRTAVAK KEALSSGLPL SDYSLGKALS2460
 2461 LGWYDQSAGT FTHPETQKQL TLKEAIMKGL FDPYDTTIVD KKAGKEISLL EAIREEIVDD2520
 2521 NAGTVKDTQT GRVHNFLEAG NLGLVKGKNF GDTLDSSLFS GRLDLGSGSY TRPSGGSSMP2580
 2581 IHEAINRNYV DRSSVSVRDP SSGQQYSYQE AVDRRIVDAD RGLIHGGGDS TSFSQGLTSG2640
 2641 HLVSSGSSRP TSGNQSRLVE QRLQLTPFAP NGGAGRSRDG RHELVDLGGG QQVQVKVVRG2700
 2701 EGGVEKGEYT DPKSGMKFTI QMHGDPVVTE TKTSVKSTSQ VHSVELEPHA EFVGIDRVRD2760
 2761 KRNNHVYSLE EARRLGLAKV DKKGKQMTRS YQAFRSNIDN AVNNGVVDSH NQKISLENAI2820
 2821 HARIIDIRNL SYHHPTHGSV DLKTAASQGL VDVTLSEVLP KGIIHPGTGE RIDIKRGIEL2880
 2881 RIIDAATGKV RDPRDNKTIT WIDILKPVYQ AIASEGVFDP TKGHHVPVTT ALNDGLINAS2940
 2941 TGNYRNSITG EDVPLSDTVD RGLIDRSTYE TITKPFFTDY RSNRKLNLVE AVRERLIDPK3000
 3001 NRTIQLSRQS IVPIAKAVQD GRIPMEIGEK LRKVDKLNFA EALGKGLIDS KQNVFTDPDT3060
 3061 GRQMSIAQAI QEGFIDTGSV QGIEGNDESN LFNVLQSSDF DETSGRIYDK KSSLHLTFND3120
 3121 AVRRGVIDGD SLLHLQATGD LLTLRDALHQ NKIDSNGKFV EGANRLKISD AVKSGRLTVI3180
 3181 ASPSEAVQAV TEGVKRRDAE GYKFRISEYD DSQAQRQSVP KFRETVTVSK LTPQYNEPGL3240
 3241 SVRMRQSTTS IGDRASKFLE DPSQLAEIQQ DFLSSLEAAQ FDTDEKVIEH PHTRQRVSVR3300
 3301 EAAETGLLDV QTGEIVNPDN GRRFSIPRAV HMKLVGGDAA KRIMEQLNMP VEEVAYATQT3360
 3361 ITSSTHRAPS PVFATASVSQ PSGGATTTRE FTRTINWHGQ PSELRNSQTD PLAAYTTVSS3420
 3421 NVTESTEDAP AWARKQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.85

Protein Overview: vab-10

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: