Protein Overview: unc-2

General Information:
Name(s) found:	unc-2 / CE34980 [WormBase]
Description(s) found: Found 18 descriptions. SHOW ALL	WBGene00006742 locus:unc-2 status:Confirmed UniProt:Q86G45 protein_id:CCD74385.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	2027 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA]
Biological Process:	response to heat [IMP] ion transport [IEA] locomotory behavior [IMP] DNA methylation [IEA] regulation of neurotransmitter levels [IMP] response to starvation [IMP] negative regulation of transforming growth factor beta receptor signaling pathway [IGI]
Molecular Function:	DNA binding [IEA] ion channel activity [IEA] N-methyltransferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPIAASEII PSPIHPRKIS INDRLFEIRT PRPGEMIKEA VQMAVWPALP RLAAEEARRE  60
   61 QKAESGTFVR KTTLSSNAPV KEKGPSSLFI FAEDNIIRRN AKAIIEWGPF EYFILLTIIG 120
  121 NCVVLSMEQH LPKNDKKALS EWLERTEPYF MGIFCLECVL KVIAFGFALH KGSYLRSGWN 180
  181 IMDFIVVVSG VVTMLPFSPA TQTANQPVDS VDLRTLRAVR VLRPLKLVSG IPSLQVVLKS 240
  241 ILCAMAPLLQ IGLLVLFAII IFAIIGLEFY SGAFHSACYN ERGEIENVSE RPMPCTNKTS 300
  301 PMGVYNCDVK GTTCLQKWIG PNYGITSFDN IGFAMITVFQ CITMEGWTTV MYYTNDSLGS 360
  361 TYNWAYFIPL IVLGSFFMLN LVLGVLSGEF AKERERVENR REFLKLRRQQ QIERELNGYL 420
  421 EWILTAEEVI LKEDRTTEEE KAAIMEARRR AANKKLKQAS KQQSTETEED FEEDEDEMEE 480
  481 EYVDEGGTVE DEFAERKKRG CCHSVGKFIK QLRIQIRIMV KTQIFYWSVI TLVFLNTCCV 540
  541 ASEHYGQPQW FTDFLKYAEF VFLGIFVVEM LLKLFAMGSR TYFASKFNRF DCVVIVGSAA 600
  601 EVIWAEVYGG SFGISVMRAL RLLRIFKLTS YWVSLRNLVR SLMNSMRSII SLLFLLFLFI 660
  661 LIFALLGMQL FGGRFNFPTM HPYTHFDTFP VALITVFQIL TGEDWNEVMY LAIESQGGIY 720
  721 SGGWPYSIYF IVLVLFGNYT LLNVFLAIAV DNLANAQELT AAEEADEKAN EIEEESEELD 780
  781 EQYQEGDHCT IDMEGKTAGD MCAVARAMDD LDEECEEEES PFGGPKPMVP YSSMFFLSPT 840
  841 NPFRVLIHSI VCTKYFEMMV MTVICLSSVS LAAEDPVDEE NPRNKVLQYM DYCFTGVFAC 900
  901 EMLLKLIDQG ILLHPGSYCR DFWNILDGIV VTCALFAFGF AGTEGSAGKN LNTIKSLRVL 960
  961 RVLRPLKTIK RIPKLKAVFD CVVNSLKNVF NILIVYFLFQ FIFAVIAVQL FNGKFFFCTD1020
 1021 KNRKFANTCH GQFFVYDNQN DPPRVEQREW RLRPFNYDNT INAMLTLFVV TTGEGWPGIR1080
 1081 QNSMDTTFED QGPSPFFRVE VALFYVMFFI VFPFFFVNIF VALIIITFQE QGEAELSEGD1140
 1141 LDKNQKQCID FALNARPRSL FMPEDKNSTK YRIWRLVTSP PFEYFIMTMI CCNTLILMMK1200
 1201 YYNNPLFYEE ILRLFNTALT AVFTVESILK ILAFGVRNYF RDGWNRFDFV TVVGSITDAL1260
 1261 VTEFGGHFVS LGFLRLFRAA RLIRLLQQGY TIRILLWTFV QSFKALPYVC LLIGMLFFIY1320
 1321 AIVGMQVFGN IWLNAATEIN RHNNFQSFFN AVILLFRCAT GEGWQDIMMA AVQGKDCARA1380
 1381 GSAEINFEKG QTCGSNVSYA YFTSFVFLSS FLMLNLFVAV IMDNFDYLTR DSSILGPHHL1440
 1441 DEFIRVWADY DPAATGRIHY SEMYEMLRIM APPVGFGKKC PYRLAYKHLI RMNMPVAEDG1500
 1501 TVHFTTTLFA LIRESLSIKM RPVEEMDEAD EELRLTLKKI WPLKAKKNMV DLVVPPNHEL1560
 1561 CFQKLTVGKI YAGLLILENY RARKSGTEVG GQGLFGGGLR SLVAAAKAAE SQHSSHTPQP1620
 1621 PEETTPIIPQ HAQQFSAAPT MSAQGSLQQM QGTSSGGGQR PYSLFNSFVD TIKSGKQDGD1680
 1681 VTDVQYQSVD QQHEKMNSTG RRLSDMFSKI RRGTSADHNP HQTEHLLAQD NRSPSSPRYR1740
 1741 SMARASPPSP AERYGHPPRY RTESPPSSRS EYQMSIRDPI IRRNRYNTME HSRSSHDPQY1800
 1801 HQDQQQQQQP HHQQHSQHLQ HSHHKTYQNH NQYSRSPIYS DDSSVAESYR REREFRRYQD1860
 1861 STPQDVSEDD DPMPTAVRAR RLPLISTMPT HYESAYQPSS YNQHLNDSYG LGTGYQRDYH1920
 1921 TSHSHSHHPT SQQQQHQPMY STSPLISPRS SHSYYTPRSS QYYEIPSPSP DIYPSYRGSA1980
 1981 SPRRYPTSTV VVAPDREGSS ARVIQAQPGS IPLSDSETED DPRWAIV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: unc-2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: