Protein Overview: CE34752

General Information:
Name(s) found:	CE34752 [WormBase]
Description(s) found: Found 15 descriptions. SHOW ALL	WBGene00016624 status:Partially_confirmed UniProt:Q95QR5 protein_id:CCD61555.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	597 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA]
Biological Process:	mRNA processing [IEA]
Molecular Function:	nucleic acid binding [IEA] RNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQGRGGYHHG FDGPKRYRRD DNADPTNPNP SIVVHVRNLH QKVTEADLLE ALSNFGPVAY  60
   61 ATCIPHSRMA LVEFEDIEGA KACVNFATSN QINVGGQGAL FNYSTSQCIE RMGFESATPN 120
  121 KVLVVTVLNA QYPIDADVIY QISNAQGKVL RVAVMHKPTV VQALVEFESM EVAKAAKHAM 180
  181 NGADIYSGCC TLKVEFAKPD RVRVQRQDKD QRDFTLPDNE SFQDTGRKTL IPAKPDDHYR 240
  241 RPYEDDRNHY DRHDYQAPSS YGYSSRGGGH SDYYGGDRGG PPHPPPSRYR DDYEDRGYAQ 300
  301 PAGGGPGCVM MIYGLEHGKI NCDMLFNILC QYGNVLRISF MRTKTETGII ELGTPEERQN 360
  361 VLDFLQGSAL FGLTLEFKPS HQECVHHLRD PFLLPDGSPS FKDYSSSRNQ RFSTPELAAK 420
  421 NRIIFPTNTL HWFNAPGTMD EQALLDLMAE KTEHKPVKID IFPSRNERSA AGTAEFETVE 480
  481 IANEVLALVN HTPVNSPYGS APFIVKWAYA TPRRWDGSGG EPPRYEEGGD GERKEGFIQP 540
  541 AHRPSPSFRG RGRGYGDSGF RRESYRGGLH GSDRYGPYPP RGGGFRGGRG RGRFDGY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..90]	PSI-BLAST	6.30103	Solution structure of RRM domain in protein BAB28521
2	View Details	[91..306]	PSI-BLAST	12.30103	NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)
3	View Details	[307..515]	PSI-BLAST	27.69897	Polypyrimidine tract-binding protein
4	View Details	[516..597]	MSA	1.469995	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
RNA binding	6.73097473547076	bayes_pls_golite062009
mRNA binding	5.29759606920196	bayes_pls_golite062009
	4.67888641618755	bayes_pls_golite062009
nucleic acid binding	3.81920018903278	bayes_pls_golite062009
poly-pyrimidine tract binding	3.11990160533699	bayes_pls_golite062009
binding	3.05116833253954	bayes_pls_golite062009
single-stranded RNA binding	2.93798024346416	bayes_pls_golite062009
snRNA binding	1.76821382294389	bayes_pls_golite062009
structural molecule activity	1.29928829870122	bayes_pls_golite062009
transcription regulator activity	1.07788694919471	bayes_pls_golite062009
DNA binding	0.978604858165557	bayes_pls_golite062009
U1 snRNA binding	0.612226940931031	bayes_pls_golite062009
mRNA 3'-UTR binding	0.591700155096213	bayes_pls_golite062009
protein binding	0.42571879933058	bayes_pls_golite062009
transcription factor activity	0.234742017105535	bayes_pls_golite062009

2

Term	Confidence	Notes
RNA binding	6.73097473547076	bayes_pls_golite062009
mRNA binding	5.29759606920196	bayes_pls_golite062009
	4.67888641618755	bayes_pls_golite062009
nucleic acid binding	3.81920018903278	bayes_pls_golite062009
poly-pyrimidine tract binding	3.11990160533699	bayes_pls_golite062009
binding	3.05116833253954	bayes_pls_golite062009
single-stranded RNA binding	2.93798024346416	bayes_pls_golite062009
snRNA binding	1.76821382294389	bayes_pls_golite062009
structural molecule activity	1.29928829870122	bayes_pls_golite062009
transcription regulator activity	1.07788694919471	bayes_pls_golite062009
DNA binding	0.978604858165557	bayes_pls_golite062009
U1 snRNA binding	0.612226940931031	bayes_pls_golite062009
mRNA 3'-UTR binding	0.591700155096213	bayes_pls_golite062009
protein binding	0.42571879933058	bayes_pls_golite062009
transcription factor activity	0.234742017105535	bayes_pls_golite062009

3

Term	Confidence	Notes
RNA binding	6.73097473547076	bayes_pls_golite062009
mRNA binding	5.29759606920196	bayes_pls_golite062009
	4.67888641618755	bayes_pls_golite062009
nucleic acid binding	3.81920018903278	bayes_pls_golite062009
poly-pyrimidine tract binding	3.11990160533699	bayes_pls_golite062009
binding	3.05116833253954	bayes_pls_golite062009
single-stranded RNA binding	2.93798024346416	bayes_pls_golite062009
snRNA binding	1.76821382294389	bayes_pls_golite062009
structural molecule activity	1.29928829870122	bayes_pls_golite062009
transcription regulator activity	1.07788694919471	bayes_pls_golite062009
DNA binding	0.978604858165557	bayes_pls_golite062009
U1 snRNA binding	0.612226940931031	bayes_pls_golite062009
mRNA 3'-UTR binding	0.591700155096213	bayes_pls_golite062009
protein binding	0.42571879933058	bayes_pls_golite062009
transcription factor activity	0.234742017105535	bayes_pls_golite062009

4

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle