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Protein Overview: tsg-101

General Information:
Name(s) found: tsg-101 / CE34675 [WormBase]
Description(s) found:
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  • WBGene00015658 locus:tsg-101 status:Partially_confirmed UniProt:O76258 protein_id:CCD64026.1 [WormBase]
  • gi|71982582|ref|NP_500364.2| Tumor Susceptibility Gene homolog family member (tsg-101) [Caenorhabditis elegans] [NCBI NR]
  • gi|33285220|gb|AAC25822.2| Tumor susceptibility gene homolog protein 101 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep111.fasta]
  • Hypothetical protein C09G12.9 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE34675 WBGene00015658 status:Partially_confirmed TR:O76258 protein_id:AAC25822.2 [wormpep150.fasta]
  • 34675 WBGene00015658 status:Partially_confirmed TR:O76258 protein_id:AAC25822.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • status:Partially_confirmed TR:O76258 protein_id:AAC25822.2 [wormpep115.fasta.reversed]
  • CE34675 WBGene00015658 locus:tsg-101 status:Partially_confirmed UniProt:O76258_CAEEL protein_id:AAC25822.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE34675 WBGene00015658 locus:tsg-101 status:Partially_confirmed UniProt:O76258_CAEEL protein_id:AAC25822.2| [wormORF-contam.fasta]
  • C09G12.9 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE34675 WBGene00015658 locus:tsg-101 status:Partially_confirmed UniProt:O76258 protein_id:AAC25822.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE34675 WBGene00015658 locus:tsg-101 status:Partially_confirmed UniProt:O76258 protein_id:CCD64026.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Tumor Susceptibility Gene homolog OS=Caenorhabditis elegans GN=tsg-101 PE=1 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 425 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    protein transport [IEALink to PubMed article]
    protein modification process [IEALink to PubMed article]
    ubiquitin cycle [IEALink to PubMed article]
    Molecular Function: small conjugating protein ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAHQVQQCL QRAGGKYADS AKKDIIGALS QFKDLSPGTD TFMFPDGKRR TAFRLKGTIP  60
   61 VYYKGACYNI PVTVYLWDTH PYYAPICYVN PTSTMVIKES EHVNKEGKVF LPYLNEWRFP 120
  121 GYDLSGLLQV MAMVFQEKCP VFARSAANSA TNASATNPSA GSSASSTPTP YPSSQPTMPT 180
  181 PYPTGSGAAP YPPSSTPYPS AGAMGYNPYM NVPQSTPYPM GASGASPYPS ASSNPAPPPP 240
  241 RPPPVTAQTS VSSSSGGTIQ ADTIRASVMS AVEEKIRAKL RERMGTNSAE MASIRTTSDE 300
  301 LREGQQKLKR MLEELETQRS SLQTACEIYT AKKAELAKAL SDAGGTDAPP IDEAIDAAFP 360
  361 LHRQIVLNYA KDLTCDDVIY SLGQSLKKRQ ITLAEYLRHV RDVSREQFIY RATMQKCRRT 420
  421 AGLPI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..141] PSI-BLAST 47.69897 Tumor susceptibility gene 101 (TSG101) UEV domain
    2 View Details [142..268] PSI-BLAST 3.522879 Sec24
    3 View Details [269..425] PSI-BLAST 34.0 No description for 2p22A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  0.45543793305446 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.181948894099648 bayes_pls_golite062009
  • protein binding
    		•  0.030781579956521 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle