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Protein Overview: unc-2

General Information:
Name(s) found: unc-2 / CE34591 [WormBase]
Description(s) found:
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  • WBGene00006742 locus:unc-2 status:Confirmed UniProt:Q7YZH2 protein_id:CCD74387.1 [WormBase]
  • gi|71995573|ref|NP_001024871.1| UNCoordinated family member (unc-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|32452978|gb|AAP82641.1| Uncoordinated protein 2, isoform d [Caenorhabditis elegans] [NCBI NR]
  • [wormpep111.fasta]
  • Uncoordinated protein 2, isoform d [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE34591 WBGene00006742 locus:unc-2 status:Confirmed TR:Q7YZH2 protein_id:AAP82641.1 [wormpep150.fasta]
  • 34591 WBGene00006742 locus:unc-2 status:Confirmed TR:Q7YZH2 protein_id:AAP82641.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • locus:unc-2 status:Confirmed TR:Q7YZH2 protein_id:AAP82641.1 [wormpep115.fasta.reversed]
  • CE34591 WBGene00006742 locus:unc-2 status:Confirmed UniProt:Q7YZH2_CAEEL protein_id:AAP82641.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE34591 WBGene00006742 locus:unc-2 status:Confirmed UniProt:Q7YZH2_CAEEL protein_id:AAP82641.1| [wormORF-contam.fasta]
  • UNCoordinated family member (unc-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE34591 WBGene00006742 locus:unc-2 status:Confirmed UniProt:Q7YZH2 protein_id:AAP82641.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE34591 WBGene00006742 locus:unc-2 status:Confirmed UniProt:Q7YZH2 protein_id:CCD74387.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of G4SFC3, Uncharacterized protein OS=Caenorhabditis elegans GN=unc-2 PE=4 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 286 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: response to heat [IMPLink to PubMed article]
    ion transport [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    DNA methylation [IEALink to PubMed article]
    regulation of neurotransmitter levels [IMPLink to PubMed article]
    response to starvation [IMPLink to PubMed article]
    negative regulation of transforming growth factor beta receptor signaling pathway [IGILink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    ion channel activity [IEALink to PubMed article]
    N-methyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARASPPSPA ERYGHPPRYR TESPPSSRSE YQMSIRDPII RRNRYNTMEH SRSSHDPQYH  60
   61 QDQQQQQQPH HQQHSQHLQH SHHKTYQNHN QYSRSPIYSD DSSVAESYRR EREFRRYQDS 120
  121 TPQDVSEDDD PMPTAVRARR LPLISTMPTH YESAYQPSSY NQHLNDSYGL GTGYQRDYHT 180
  181 SHSHSHHPTS QQQQHQPMYS TSPLISPRSS HSYYTPRSSQ YYEIPSPSPD IYPSYRGSAS 240
  241 PRRYPTSTVV VAPDREGSSA RVIQAQPGSI PLSDSETEDD PRWAIV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..182] deduced N/A No confident structure predictions are available.
    2 View Details [183..286] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle