Protein Overview: unc-53

General Information:
Name(s) found:	unc-53 / CE34019 [WormBase]
Description(s) found: Found 20 descriptions. SHOW ALL	WBGene00006788 locus:unc-53 Adapter protein unc-53 status:Partially_confirmed UniProt:Q7YSI9 protein_id:CAD91632.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	1520 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	mating behavior [IMP] mesodermal cell migration [IGI] signal transduction [IPI] backward locomotion [IMP] oviposition [IMP] axon guidance [IMP] positive regulation of axon extension [IMP] actin cytoskeleton organization [ISS] positive regulation of multicellular organism growth [IMP] positive regulation of cell migration [IGI] determination of muscle attachment site [IMP]
Molecular Function:	actin filament binding [ISS] nucleotide binding [IEA][ISS] protein binding [IPI] nucleoside-triphosphatase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPAVSKLPS PRVATSATAS ATNPNSNFPQ MSTSRLQTPQ SRISKIDSSK IGIKPKTSGL  60
   61 KPPSSSTTSS NNTNSFRPSS RSSGNNNVGS TISTSAKSLE SSSTYSSISN LNRPTSQLQK 120
  121 PSRPQTQLVR VATTTKIGSS KLAAPKAVST PKLASVKTIG AKQEPDNSGG GGGGMLKLKL 180
  181 FSSKNPSSSS NSPQPTRKAA AVPQQQTLSK IAAPVKSGLK PPTSKLGSAT SMSKLCTPKV 240
  241 SYRKTDAPII SQQDSKRCSK SSEEESGYAG FNSTSPTSSS TEGSLSMHST SSKSSTSDEK 300
  301 SPSSDDLTLN ASIVTAIRQP IAATPVSPNI INKPVEEKPT LAVKGVKSTA KKDPPPAVPP 360
  361 RDTQPTIGVV SPIMAHKKLT NDPVISEKPE PEKLQSMSID TTDVPPLPPL KSVVPLKMTS 420
  421 IRQPPTYDVL LKQGKITSPV KSFGYEQSSA SEDSIVAHAS AQVTPPTKTS GNHSLERRMG 480
  481 KNKTSESSGY TSDAGVAMCA KMREKLKEYD DMTRRAQNGY PDNFEDSSSL SSGISDNNEL 540
  541 DDISTDDLSG VDMATVASKH SDYSHFVRHP TSSSSKPRVP SRSSTSVDSR SRAEQENVYK 600
  601 LLSQCRTSQR GAAATSTFGQ HSLRSPGYSS YSPHLSVSAD KDTMSMHSQT SRRPSSQKPS 660
  661 YSGQFHSLDR KCHLQEFTST EHRMAALLSP RRVPNSMSKY DSSAAALNAS GMSRSMILLE 720
  721 SLSPRPPRRH QSPADSCIIT ASPSAPRRSH SPRGPTARIP LSLASSPVHV NNNWGSYSAR 780
  781 SRGGSSTGIY GETFQLHRLS DEKSPAHSAK SEMGSQLSLA STTAYGSLNE KYEHAIRDMA 840
  841 RDLECYKNTV DSLTKKQENY GALFDLFEQK LRKLTQHIDR SNLKPEEAIR FRQDIAHLRD 900
  901 ISNHLASNSA HANEGAGELL RQPSLESVAS HRSSMSSSSK SSKQEKISLS SFGKNKKSWI 960
  961 RSSLSKFTKK KNKNYDEAHM PSISGSQGTL DNIDVIELKQ ELKERDSALY EVRLDNLDRA1020
 1021 REVDVLRETV NKLKTENKQL KKEVDKLTNG PATRASSRAS IPVIYDDEHV YDAACSSTSA1080
 1081 SQSSKRSSGC NSIKVTVNVD IAGEISSIVN PDKEIIVGYL AMPTSQSCWK DIDVSILGLF1140
 1141 EVYLSRIDVE HQLGIDARDS ILGYQIGELR RVIGDSTTMI TSHPTDILTS STTIRMFMHG1200
 1201 AAQSRVDSLV LDMLLPKQMI LQLVKSILTE RRLVLAGATG IGKSKLAKTL AAYVSIRTNQ1260
 1261 SEDSIVNISI PENNKEELLQ VERRLEKILR SKESCIVILD NIPKNRIAFV VSVFANVPLQ1320
 1321 NNEGPFVVCT VNRYQIPELQ IHHNFKMSVM SNRLEGFILR YLRRRAVEDE YRLTVQMPSE1380
 1381 LFKIIDFFPI ALQAVNNFIE KTNSVDVTVG PRACLNCPLT VDGSREWFIR LWNENFIPYL1440
 1441 ERVARDGKKT FGRCTSFEDP TDIVSEKWPW FDGENPENVL KRLQLQDLVP SPANSSRQHF1500
 1501 NPLESLIQLH ATKHQTIDNI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.67

Protein Overview: unc-53

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: