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Protein Overview: fbxa-1

General Information:
Name(s) found: fbxa-1 / CE33881 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00021856 status:Partially_confirmed UniProt:Q95XK4 protein_id:CCD73838.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 766 amino acids

    Gene Ontology:
    Cellular Component: protein serine/threonine phosphatase complex [IEALink to PubMed article]
    Biological Process: protein amino acid dephosphorylation [IEALink to PubMed article]
    Molecular Function: protein serine/threonine phosphatase activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQTSEPMAR TPIQFGENMR ITVAASQGGR RYMEDRCVIH TERINNGLLD WTFVGVFDGH  60
   61 GGEHASEYVR RHLLMNITKN QKFESNSDED ILEAIRQGFL MTHEQMRHVY DEWPYTASGY 120
  121 PSTAGTTVSC VFIRNGKLYT GHVGDSAIFL GTVENGELHS RPLTTDHKPE SVHEQLRIAK 180
  181 AGGETAVKSG VTRVVWKRPQ KMSQFMMMTS NSNEQKHHQN PQIMENIPFL SVARSLGDLW 240
  241 SYNEKTNMFI VSPEPDLGVH RLTGNDFCLV LASDGMTNVM TGDQAISIVF KEEEMVEIHE 300
  301 EINRNHSRCV LRSALQKWRS LRADNVTIAT VIFDIEPIKY TDAEMLMKVG KYVNASQVLT 360
  361 DRPDAMLKVS KNENILLSTQ RTPIIYNGSK DVNFCRVTYK GPGFRTHEDE LLEERRNLMS 420
  421 KFGGVDGGAA IAIAGGPPVD ARRGDTTGKD ENNVKYDVNG EEDDIINDIT TEEEASQEID 480
  481 LSLRLVQRST AVTIIESPNR PPRPHAPRPV FIDDSIIEEE NDGNLDEKSL IGVQITPSRT 540
  541 SPGHCTVRRV KAEAVRKLRT PKMSTMDESS SSSTPPDRRI TRSASKGLKT PPTPEPPRGI 600
  601 IGVNPNLTAD AVLLLTPRRR RSTRIQNSCA SAAAPGAASL STEKLTQSSR KRARTCAVGA 660
  661 ASGVTPVVAS LTLQDHQLLR PHTHAPPPTP SRSAPSSPSS KKCEISSSLK TSKSAKASSL 720
  721 SKLDDGIIRV SEIADEEDDD DVTMMRGPPS KMRRFFGYMK KMVWGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..423] PSI-BLAST 88.221849 CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION
    2 View Details [424..568] deduced N/A No confident structure predictions are available.
    3 View Details [569..766] MSA 6.200994 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  7.29765002420868 bayes_pls_golite062009
  • phosphatase activity
    		•  6.84540130415879 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.63839066304808 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.76293366458633 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  5.66354576593165 bayes_pls_golite062009
  • hydrolase activity
    		•  4.10826723952347 bayes_pls_golite062009
  • binding
    		•  1.74689317666387 bayes_pls_golite062009
  • catalytic activity
    		•  1.53401212718168 bayes_pls_golite062009
  • protein binding
    		•  0.425331902048676 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle