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Protein Overview: nhr-1

General Information:
Name(s) found: nhr-1 / CE33812 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00003600 locus:nhr-1 Nuclear hormone receptor family member nhr-1 status:Confirmed UniProt:Q21878 protein_id:CCD70297.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 440 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGTLADQLQ SHLANYGQPM VNSQRNEDPS MYMNGSAASV SHTNGSSSMG NDQKFPSYKR  60
   61 MAQRRKVPEG ELCAVCSDLA TGYHYGVASC NGCKTFFRRT IVSEQTFICQ YNGNCDVNKN 120
  121 IRCACRHCRF NKCLLVGMDA KAIQNDRDRI GPTKKIKMSS GSDDEQATTP HRLQDQEIID 180
  181 QLTQVEGLCQ ELRRCIIPEV TGVTHALTSP CLLFETTDLK VDVSLTNTIF KELFPASMND 240
  241 IRMWNIREMR ICIEWAKTFD VYQRLNLFDQ FALVRNFAFA FNLLNRVFYS PDHGPDKIVF 300
  301 QNGAFIMRQP QQQVQLSGCR PIYTRQMDEI MIPFRKLQLS VAEFATFKAA LFFNPDALDL 360
  361 SPQAKQEVFE ERNKYLGGLF TCITQKIGIP TGVQKYGSLL MMTASIQNIL AQNEENMQVM 420
  421 ELFKNWEVDP FVKELCMKRA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..181] PSI-BLAST 24.30103 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
    2 View Details [182..440] PSI-BLAST 45.69897 Crystal structure of the agonist-bound ligand-binding domain of Biomphalaria glabrata RXR


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle