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View Structure Prediction Details

Protein: nhr-1
Organism: Caenorhabditis elegans
Length: 440 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-1.

Description E-value Query
Range
Subject
Range
gi|5702091 - gi|5702091|gb|AAD47137.1|AF061181_1 green fluorescent protein-estrogen receptor alpha fusion [Mammal...
308.0 [0..4] [439..383]

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Predicted Domain #1
Region A:
Residues: [1-181]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGTLADQLQ SHLANYGQPM VNSQRNEDPS MYMNGSAASV SHTNGSSSMG NDQKFPSYKR  60
   61 MAQRRKVPEG ELCAVCSDLA TGYHYGVASC NGCKTFFRRT IVSEQTFICQ YNGNCDVNKN 120
  121 IRCACRHCRF NKCLLVGMDA KAIQNDRDRI GPTKKIKMSS GSDDEQATTP HRLQDQEIID 180
  181 Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.30103
Match: 2a66A
Description: Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [182-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTQVEGLCQE LRRCIIPEVT GVTHALTSPC LLFETTDLKV DVSLTNTIFK ELFPASMNDI  60
   61 RMWNIREMRI CIEWAKTFDV YQRLNLFDQF ALVRNFAFAF NLLNRVFYSP DHGPDKIVFQ 120
  121 NGAFIMRQPQ QQVQLSGCRP IYTRQMDEIM IPFRKLQLSV AEFATFKAAL FFNPDALDLS 180
  181 PQAKQEVFEE RNKYLGGLFT CITQKIGIPT GVQKYGSLLM MTASIQNILA QNEENMQVME 240
  241 LFKNWEVDPF VKELCMKRA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.69897
Match: 1xiuA
Description: Crystal structure of the agonist-bound ligand-binding domain of Biomphalaria glabrata RXR
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle