Protein Overview: unc-53

General Information:
Name(s) found:	unc-53 / CE33783 [WormBase]
Description(s) found: Found 19 descriptions. SHOW ALL	WBGene00006788 locus:unc-53 Adapter protein unc-53 status:Partially_confirmed UniProt:Q7YSI9 protein_id:CAD89730.3 [WormBase]
Organism:	Caenorhabditis elegans
Length:	1654 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	mating behavior [IMP] mesodermal cell migration [IGI] signal transduction [IPI] backward locomotion [IMP] oviposition [IMP] axon guidance [IMP] positive regulation of axon extension [IMP] actin cytoskeleton organization [ISS] positive regulation of multicellular organism growth [IMP] positive regulation of cell migration [IGI] determination of muscle attachment site [IMP]
Molecular Function:	actin filament binding [ISS] nucleotide binding [IEA][ISS] protein binding [IPI] nucleoside-triphosphatase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTSNVELIP IYTDWANRHL SKGSLSKSIR DISNDFRDYR LVSQLINVIV PINEFSPAFT  60
   61 KRLAKITSNL DGLETCLDYL KNLGLDCSKL TKTDIDSGNL GAVLQLLFLL STYKQKLRQL 120
  121 KKDQKKLEQL PTSIMPPAVS KLPSPRVATS ATASATNPNS NFPQMSTSRL QTPQSRISKI 180
  181 DSSKIGIKPK TSGLKPPSSS TTSSNNTNSF RPSSRSSGNN NVGSTISTSA KSLESSSTYS 240
  241 SISNLNRPTS QLQKPSRPQT QLVRVATTTK IGSSKLAAPK AVSTPKLASV KTIGAKQEPD 300
  301 NSGGGGGGML KLKLFSSKNP SSSSNSPQPT RKAAAVPQQQ TLSKIAAPVK SGLKPPTSKL 360
  361 GSATSMSKLC TPKVSYRKTD APIISQQDSK RCSKSSEEES GYAGFNSTSP TSSSTEGSLS 420
  421 MHSTSSKSST SDEKSPSSDD LTLNASIVTA IRQPIAATPV SPNIINKPVE EKPTLAVKGV 480
  481 KSTAKKDPPP AVPPRDTQPT IGVVSPIMAH KKLTNDPVIS EKPEPEKLQS MSIDTTDVPP 540
  541 LPPLKSVVPL KMTSIRQPPT YDVLLKQGKI TSPVKSFGYE QSSASEDSIV AHASAQVTPP 600
  601 TKTSGNHSLE RRMGKNKTSE SSGYTSDAGV AMCAKMREKL KEYDDMTRRA QNGYPDNFED 660
  661 SSSLSSGISD NNELDDISTD DLSGVDMATV ASKHSDYSHF VRHPTSSSSK PRVPSRSSTS 720
  721 VDSRSRAEQE NVYKLLSQCR TSQRGAAATS TFGQHSLRSP GYSSYSPHLS VSADKDTMSM 780
  781 HSQTSRRPSS QKPSYSGQFH SLDRKCHLQE FTSTEHRMAA LLSPRRVPNS MSKYDSSAAA 840
  841 LNASGMSRSM ILLESLSPRP PRRHQSPADS CIITASPSAP RRSHSPRGPT ARIPLSLASS 900
  901 PVHVNNNWGS YSARSRGGSS TGIYGETFQL HRLSDEKSPA HSAKSEMGSQ LSLASTTAYG 960
  961 SLNEKYEHAI RDMARDLECY KNTVDSLTKK QENYGALFDL FEQKLRKLTQ HIDRSNLKPE1020
 1021 EAIRFRQDIA HLRDISNHLA SNSAHANEGA GELLRQPSLE SVASHRSSMS SSSKSSKQEK1080
 1081 ISLSSFGKNK KSWIRSSLSK FTKKKNKNYD EAHMPSISGS QGTLDNIDVI ELKQELKERD1140
 1141 SALYEVRLDN LDRAREVDVL RETVNKLKTE NKQLKKEVDK LTNGPATRAS SRASIPVIYD1200
 1201 DEHVYDAACS STSASQSSKR SSGCNSIKVT VNVDIAGEIS SIVNPDKEII VGYLAMPTSQ1260
 1261 SCWKDIDVSI LGLFEVYLSR IDVEHQLGID ARDSILGYQI GELRRVIGDS TTMITSHPTD1320
 1321 ILTSSTTIRM FMHGAAQSRV DSLVLDMLLP KQMILQLVKS ILTERRLVLA GATGIGKSKL1380
 1381 AKTLAAYVSI RTNQSEDSIV NISIPENNKE ELLQVERRLE KILRSKESCI VILDNIPKNR1440
 1441 IAFVVSVFAN VPLQNNEGPF VVCTVNRYQI PELQIHHNFK MSVMSNRLEG FILRYLRRRA1500
 1501 VEDEYRLTVQ MPSELFKIID FFPIALQAVN NFIEKTNSVD VTVGPRACLN CPLTVDGSRE1560
 1561 WFIRLWNENF IPYLERVARD GKKTFGRCTS FEDPTDIVSE KWPWFDGENP ENVLKRLQLQ1620
 1621 DLVPSPANSS RQHFNPLESL IQLHATKHQT IDNI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: unc-53

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: