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Protein Overview: pyp-1

General Information:
Name(s) found: pyp-1 / CE33768 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00008149 locus:pyp-1 inorganic pyrophosphatase status:Confirmed UniProt:Q18680 protein_id:CAD89726.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 407 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    phosphate metabolic process [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: magnesium ion binding [IEALink to PubMed article]
    inorganic diphosphatase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGCAVSQESA IATVSSSSNT ATTSTSSSNT SQKWATSRTS RPVTNVTQVS AIHTTSMDSG  60
   61 SSTVQLPSPR GSLTTAVSTS SSGAQRQMSA NSERSLHTRL PLSETAVILQ SQAVKMSTGA 120
  121 GDSAVYEAVE RGSLYSLDYR VYIKGPQGIV SPWHDIPLFA NKDKRVYNMI VEIPRWTNAK 180
  181 MEMATKEPFS PIKQDEKKGV ARFVHNIFPH KGYIWNYGAL PQTWEDPNHV VPDTGAKGDN 240
  241 DPIDVIEVGS KVAGRGAVLQ VKVLGTLALI DEGETDWKLV AIDVNDENAD KLNDIDDVEK 300
  301 VYPGLLAASV EWFRNYKIPA GKPANEFAFN GEFKNREYAE KVIDETNEYW KTLIKEANPS 360
  361 LNTVSRVPEA VHQGTDEAAA TAIGATPEHG ANAPLPGDVD KWHFVQG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..124] MSA 16.063997 View MSA. No confident structure predictions are available.
    2 View Details [125..407] PSI-BLAST 100.0 Inorganic pyrophosphatase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • inorganic diphosphatase activity
    		•  2.74116819406619 bayes_pls_golite062009
  • binding
    		•  1.77492613217844 bayes_pls_golite062009
  • catalytic activity
    		•  1.33262120571864 bayes_pls_golite062009
  • protein binding
    		•  0.38607803003281 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.354425639853757 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.334860448536013 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.333575715544697 bayes_pls_golite062009
  • hydrolase activity
    		•  0.0110854177718558 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle