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Protein Overview: egl-27

General Information:
Name(s) found: egl-27 / CE33268 [WormBase]
Description(s) found:
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  • WBGene00001194 locus:egl-27 Egg-laying defective protein 27 status:Confirmed UniProt:Q09228 protein_id:CCD62845.1 [WormBase]
  • gi|71980996|ref|NP_001021912.1| EGg Laying defective family member (egl-27) [Caenorhabditis elegans] [NCBI NR]
  • gi|27885098|gb|AAO26017.1| Egg laying defective protein 27, isoform c [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • Egg laying defective protein 27, isoform c [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE33268 WBGene00001194 locus:egl-27 status:Confirmed TR:Q86LT4 protein_id:AAO26017.1 [wormpep150.fasta]
  • 33268 WBGene00001194 locus:egl-27 status:Partially_confirmed TR:Q86LT4 protein_id:AAO26017.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE33268 WBGene00001194 locus:egl-27 status:Partially_confirmed TR:Q86LT4 protein_id:AAO26017.1 [wormpep132.fasta]
  • 33268 WBGene00001194 locus:egl-27 status:Confirmed TR:Q86LT4 protein_id:AAO26017.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:egl-27 status:Partially_confirmed TR:Q86LT4 protein_id:AAO26017.1 [wormpep115.fasta.reversed]
  • CE33268 WBGene00001194 locus:egl-27 status:Confirmed UniProt:Q09228 protein_id:AAO26017.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE33268 WBGene00001194 locus:egl-27 status:Confirmed UniProt:Q09228 protein_id:AAO26017.1| [wormORF-contam.fasta]
  • EGg Laying defective family member (egl-27) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE33268 WBGene00001194 locus:egl-27 status:Confirmed SW:Q09228 protein_id:AAO26017.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE33268 WBGene00001194 locus:egl-27 status:Confirmed UniProt:Q09228 protein_id:CCD62845.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE33268 WBGene00001194 locus:egl-27 status:Confirmed UniProt:Q09228 protein_id:CCD62845.1 Egg-laying defective protein 27 [wormpep246-ecoli-contam.fasta]
  • Isoform of Q09228, Isoform c of Egg-laying defective protein 27 OS=Caenorhabditis elegans GN=egl-27 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 612 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    NuRD complex [ISSLink to PubMed article]
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    body morphogenesis [IMPLink to PubMed article]
    mesoderm development [IMPLink to PubMed article]
    epidermis development [IMPLink to PubMed article]
    regulation of asymmetric cell division [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    cell adhesion [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [ISSLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    oviposition [IMPLink to PubMed articleLink to PubMed article]
    Wnt receptor signaling pathway [IMPLink to PubMed article]
    cell fate specification [IMPLink to PubMed article]
    regulation of cell migration [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSETPDRRSP STVSNGAPNL TAEETPTKKL NGSVKRAPKR PLHNGVINNV EKSNSSEEPA  60
   61 SPTTPPPTLT NGLTNGHGPE SSTPNGETIS KRMKVEPSYD DDDDEEEGKM TIDEGDDDPM 120
  121 PVLNGFKKEE SVEEIKLELN GTIKKENGVE TDPTTPTCSM EAENEVCETP AVVSVEIRDE 180
  181 TNGETNSDLK DDENVEPDSP EDTFELGSNV EFETKNAMFV RSIVRSCGPR CARTDLIFKI 240
  241 KVGGVWEKSI KEKEERKKVH LQNQRIQDSE KVAIQQNQIK KEQQQSQPTP QQIHQQQAQQ 300
  301 NAQHLQQLQQ AVMLGHLPPE VLRQMMPPQF GVDPTAILMQ QMMAGQQSQG VNAAFQHQMA 360
  361 LQQQLEAHQV QLMMAHQHQQ KMIAEQQQQQ RHAAAQQLRE REQREQRERE RERQHQQQAQ 420
  421 QALHQQQQQH AAAAANQLNP AMMQMMALMA NSAASQQDIA RLMEMAAQQQ QQQQQAAQAQ 480
  481 AQRDQERERR EREAREREAA REREREQAAR EAAARDQAAR EHAQAVQAAA AAAQQAQALT 540
  541 PDMQHMHLLQ QLMLNPALMM QLQQAQAQQQ QQQPQVTNPL QMLQHGMAAQ SANQAEMMRR 600
  601 IHPEPAMRPQ HQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..78] PSI-BLAST 9.69897 Tropomyosin
    2 View Details [79..412] PSI-BLAST 15.09691 Heavy meromyosin subfragment
    3 View Details [413..612] FFAS03 1.65 BRCA2 helical domain; BRCA2 tower domain; OB-fold domains of BRCA2


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle