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Protein Overview: nhr-88

General Information:
Name(s) found: nhr-88 / CE33143 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00003678 locus:nhr-88 status:Confirmed UniProt:H2KZA1 protein_id:CCD67148.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 593 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: DNA integration [IEALink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    transposition, DNA-mediated [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    transposase activity [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFAPSTVYTY GHHGSGTDED DGQQVMPGMD NGDGQCMVCG DRSAGKHYGV MACYGCKGFF  60
   61 RRTIRSQQTY TCRFTQKCAI DKDQRNACRY CRFQRCLTVG MEPEAIRPDR DVIGKQKNPR 120
  121 KKKMKSDTNS GSIDASLPSP NGCDSPVSNN EDVILSFLLD VEDQATCGNN HITMPIGISM 180
  181 MMKNDPDFDV STLFHSQYVR NQESFPITYA VGRTASVEQL IAALRRYVLS AVHWIDALFN 240
  241 LAHLTEIHDK TTLLKSVIGP FTIFNIAART AQISDGDLIC LCNKSTINRQ PARHLLDTNL 300
  301 VGNNFVGRVI DDLVFPTKKL ALTNPEITIL SALIILDPDA RGLSQETSQA LLGIRDRVQN 360
  361 ALFNLIRDNS NNMTSVTSRF GNLLLLFPPL AKLSSLIGEN VQLAKMFGIP IDSLLVELYV 420
  421 DADSPELISQ GSHARERSDV STQTASLEGA SASMTPDVTS SEFVKMEQNE SPSSSEEPMC 480
  481 IGAPATSSAN AVATNLAADL LGLLPNFDAT GLDLASAAAA AATSVNYSHF YGFGNLGGSL 540
  541 DDSSSSGTGS VGSFAPHSAP PISNNVNPFA VHGFFDNSAP NTGVVHNQPF RFV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] PSI-BLAST 30.522879 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
    2 View Details [109..422] PSI-BLAST 32.522879 hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A
    3 View Details [423..593] MSA 16.302997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle