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Protein Overview: hum-2

General Information:
Name(s) found: hum-2 / CE33076 [WormBase]
Description(s) found:
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  • WBGene00002036 locus:hum-2 status:Confirmed UniProt:Q8I7K3 protein_id:CCD68604.1 [WormBase]
  • gi|71992994|ref|NP_001023887.1| Heavy chain, Unconventional Myosin family member (hum-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|27374506|gb|AAO12438.1| Heavy chain, unconventional myosin protein 2, isoform e [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • Heavy chain, unconventional myosin protein 2, isoform e [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE33076 WBGene00002036 locus:hum-2 status:Confirmed TR:Q8I7K3 protein_id:AAO12438.1 [wormpep150.fasta]
  • 33076 WBGene00002036 locus:hum-2 status:Confirmed TR:Q8I7K3 protein_id:AAO12438.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • locus:hum-2 status:Confirmed TR:Q8I7K3 protein_id:AAO12438.1 [wormpep115.fasta.reversed]
  • CE33076 WBGene00002036 locus:hum-2 status:Confirmed UniProt:Q8I7K3_CAEEL protein_id:AAO12438.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE33076 WBGene00002036 locus:hum-2 status:Confirmed UniProt:Q8I7K3_CAEEL protein_id:AAO12438.1| [wormORF-contam.fasta]
  • Heavy chain, Unconventional Myosin family member (hum-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE33076 WBGene00002036 locus:hum-2 status:Confirmed UniProt:Q8I7K3 protein_id:AAO12438.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE33076 WBGene00002036 locus:hum-2 status:Confirmed UniProt:Q8I7K3 protein_id:CCD68604.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of Q17383, Heavy chain, Unconventional Myosin OS=Caenorhabditis elegans GN=hum-2 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 440 amino acids

    Gene Ontology:
    Cellular Component: myosin complex [IEALink to PubMed article]
    Biological Process: NONE FOUND
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    protein binding [IPILink to PubMed article]
    nucleoside-triphosphatase activity [IEALink to PubMed article]
    motor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLNDKLTRQ SEELAEARAQ LRGYSGPLGL ENASDEEIIR LEAFEKGSIK HSGFLEVYNV  60
   61 PEFARIIVCE LKPTLARLLT KNLPAYLLVA AFRNHDEKRD ETALTGLFSS VHLVLKDTIS 120
  121 RSHDLDLLSL WLVNLWRLFN LLRQYSGEDS QPEWHVANTE TQNSYRFKAY DVAPIRDQLK 180
  181 LRIEECYTSL MKKAIEHVLS PKIVPGILQH ESSSDLMTAG QERRDRNSGS VESQRKSLDD 240
  241 LLQFMEIVHT KLTTYGGDDI VVKQVIGQMA RWMCALALNY MMFRRELCNF EKAIQIKHNV 300
  301 TQIQNWLNAK GLSDCRDHFE PLVQACHLLQ SRKDPSNLDT LCGEMTSRLK PRQVVAILQH 360
  361 YDPSDEMEDG LSPEFLVQIQ KKLNERAIAN NDPIEDKDKL IMLGTYLPPF DTQPFSYSDF 420
  421 PLETLSLPSC LHMQSVCRLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..440] PSI-BLAST 81.522879 Myosin V cargo binding domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle