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Protein Overview: zyg-12

General Information:
Name(s) found: zyg-12 / CE32088 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00006997 locus:zyg-12 Zygote defective protein 12 status:Confirmed UniProt:Q23529 protein_id:CCD73211.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 736 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    centrosome [IDALink to PubMed article]
    Biological Process: centrosome localization [IMPLink to PubMed article]
    pronuclear migration [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    nucleus localization [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: dynein light intermediate chain binding [IPILink to PubMed article]
    protein self-association [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDLTNKESE SSDNGNSKYE DSIDGREVGT SKPFKEERSL EDLQADLADM AVWMEGLDAT  60
   61 KLPLNDPQLL CNGRAFSEVL HNVDKNFFTD GWLETMPENR TTNIMVFRSC TRKLWRKMFD 120
  121 YVNHINRTVV SSRWTDIHER IDGIYESDLP AMVNLGMAVV TLAHIGKNAK RFVDYSKALT 180
  181 STHKSMMSNV AKMVTTVIDE MPENPCFHEI SELHGSQSEL NSLSESSGKL NGNGSSERRS 240
  241 NADQILVDAE LEIERLRTET ENQRKEIERL TKSFETAQHD MSSNSESGDI SILEKQNEEL 300
  301 RQKRRELEEK NLELDAAVDQ FKGIVFELTN ENDVLRRSDK ERQRLQTVLD AAQSDLDEWK 360
  361 TVANQYQKEA ELSKQQDKEI KELLSQNKAL KSRLDHHVKS ATLEDANKNG IAQLRTQVGG 420
  421 LTALNTELKA SLDSKKRCVE QLEIQLIQHK EKVKELEDRK DELIEERNRL ENQLIFKEAV 480
  481 TPRSLHESMF EAGNLSFEPF SEKNTLPLEI ENKRLTERIQ ELESLEPLKG ELITLKSKNG 540
  541 VLEEEKLFAT KQIEELQQQI EDLQENLLKN QEHASGDVVG LKIQLEKAEV EAQQMREAKM 600
  601 RAETNQAQVD EILKKRTAEL EVNATALQKA KAVIDELEYN SRPVSEDSMT SVQAFKEMKE 660
  661 ENEKLRQKVE KLEIELNTVT QGFEQENRLL TSASHQQVLN RSIDEVMSMR AHAGSEEPQT 720
  721 LLDTQKMSGA LPWRFS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] PSI-BLAST 21.522879 The solution structure of RSGI RUH-026, conserved domain of HOOK1 protein from mouse
    2 View Details [101..485] PSI-BLAST 17.0 Heavy meromyosin subfragment
    3 View Details [486..736] PSI-BLAST 8.39794 Tropomyosin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle