Protein Overview: obr-3

General Information:
Name(s) found:	obr-3 / CE31672 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00014215 locus:obr-3 status:Partially_confirmed UniProt:G5EC19 protein_id:CAA94223.2 [WormBase] gi\|25152502\|ref\|NP_741923.1\| Oxysterol Binding protein (OSBP) Related family member (obr-3) [Caenorhabditis elegans] [NCBI NR] gi\|22265953\|emb\|CAA94223.2\| C. elegans protein ZK1086.1a, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|22265807\|emb\|CAD44120.1\| C. elegans protein ZK1086.1a, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] [wormpep88.fasta] CE31672 WBGene00014215 locus:obr-3 Yeast hypothetical protein YHG1 like status:Partially_confirmed TR:Q23395 protein_id:CAA94223.2 [wormpep150.fasta] 31672 WBGene00014215 locus:obr-3 Yeast hypothetical protein YHG1 like status:Partially_confirmed TR:Q23395 protein_id:CAA94223.2 [wormpep130-phg-ecoli-orf-rand.fasta] oxysterol binding protein like (XO418) [Caenorhabditis elegans]gi\|22265953\|emb\|CAA94223.2\| Hypothetical protein ZK1086.1a [Caenorhabditis elegans]gi\|22265807\|emb\|CAD44120.1\| Hypothetical protein ZK1086.1a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] Yeast hypothetical protein YHG1 like status:Partially_confirmed TR:Q23395 protein_id:CAA94223.2 [wormpep115.fasta.reversed] CE31672 WBGene00014215 locus:obr-3 Yeast hypothetical protein YHG1 like status:Partially_confirmed UniProt:Q23395_CAEEL protein_id:CAD44120.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE31672 WBGene00014215 locus:obr-3 Yeast hypothetical protein YHG1 like status:Partially_confirmed UniProt:Q23395_CAEEL protein_id:CAD44120.1\| [wormORF-contam.fasta] Oxysterol Binding protein (OSBP) Related family member (obr-3) [Caenorhabditis elegans] [nr-271106-contam.fasta] Hypothetical protein ZK1086.1a [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE31672 WBGene00014215 locus:obr-3 Yeast hypothetical protein YHG1 like status:Partially_confirmed UniProt:Q23395 protein_id:CAD44120.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] CE31672 WBGene00014215 locus:obr-3 Yeast hypothetical protein YHG1 like status:Partially_confirmed UniProt:G5EC19 protein_id:CAA94223.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE31672 WBGene00014215 locus:obr-3 status:Partially_confirmed UniProt:G5EC19 protein_id:CAA94223.2 [wormpep246-ecoli-contam.fasta] Isoform of Q8MPR9, Oxysterol Binding protein (OSBP) Related OS=Caenorhabditis elegans GN=obr-3 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	733 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	regulation of multicellular organism growth [IMP] transforming growth factor beta receptor signaling pathway [IMP] steroid metabolic process [IEA]
Molecular Function:	protein binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEFDENSRK SLKKQKKEYR DEKKRVNDEL LSALRDPTVV VMADTLKIRG ALKRWNRYYC  60
   61 VLKPGLLILY KHKKADRGDW VGTVLLNHCE LIERPSKKDG FCFKLFHPMD MSIWGNRGPL 120
  121 GQSFGSFTLN PLNTSFLICR APSDQAGRCW MDALELSFKC TGLLKKTMNE LDDKNGDSSM 180
  181 NDGQRDESRM SRDSDGDDTR ELAVSETDAE KHFQEIDDVQ DEDHEDGKMS ETSDTIREAF 240
  241 TESAWIPSPK EVFGPDGSLT EEVGEENKSL IWTLLKQIRP GMDLSKVVLP TFILEPRSFL 300
  301 EKLADYYYHA DLISEAVAEP DPFQRIVKVT KFFLSGFYKK PKGLKKPYNP ILGETFRCKW 360
  361 EHPDGSTTFY MAEQVSHHPP VSSLFITNRK AGFNISGTIL AKSKYYGNSL SAILAGKLRL 420
  421 TLLNLGETYI VNLPYANCKG IMIGTMTMEL GGEVNIECEK TGYRTTLDFK LKPMLGGAYN 480
  481 QIEGSIKYGS DRLASIEGAW DGVIRIKGPD GKKELWNPTP EVIKTRLPRY EINMDEQGEW 540
  541 ESAKLWRHVT EAISNEDQYK ATEEKTALEN DQRARAKSGI PHETKFFKKQ HGDDYVYIHA 600
  601 DYRPWDNNND IQQIENNYVV KTISRHSKRK TGNSEQLGSD NTSEASESDE EVIEPKIKKK 660
  661 EIVPAKSKPI TPEVADERIK EMERKFELAI RRMEAANERQ SSRTLNAIQS TLLFVFVVTS 720
  721 VVQSIFMFFM LRK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
binding	2.86147407357315	bayes_pls_golite062009
protein binding	2.12168271674167	bayes_pls_golite062009
molecular transducer activity	1.34134699517825	bayes_pls_golite062009
signal transducer activity	1.34134699517825	bayes_pls_golite062009
transporter activity	1.28986800087234	bayes_pls_golite062009
transcription regulator activity	1.10315055505849	bayes_pls_golite062009
phospholipid binding	1.09683218092034	bayes_pls_golite062009
receptor activity	1.02045773197699	bayes_pls_golite062009
transmembrane receptor activity	0.990048359575281	bayes_pls_golite062009
nucleic acid binding	0.870327630723237	bayes_pls_golite062009
DNA binding	0.856684960067851	bayes_pls_golite062009
receptor binding	0.84825890337371	bayes_pls_golite062009
substrate-specific transporter activity	0.79883446648737	bayes_pls_golite062009
oxysterol binding	0.792005176778139	bayes_pls_golite062009
clathrin binding	0.768496041585918	bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase signaling protein activity	0.740468760397673	bayes_pls_golite062009
structural molecule activity	0.731721560204237	bayes_pls_golite062009
phosphoinositide binding	0.71817045430443	bayes_pls_golite062009
protein domain specific binding	0.51731521446502	bayes_pls_golite062009
insulin receptor binding	0.34801451897076	bayes_pls_golite062009
cytoskeletal protein binding	0.268141992393579	bayes_pls_golite062009
protein complex binding	0.22543440052247	bayes_pls_golite062009
lipid binding	0.179561240451969	bayes_pls_golite062009
SH2 domain binding	0.13752708274522	bayes_pls_golite062009
hydrolase activity	0.0955091952069367	bayes_pls_golite062009
actin binding	0.0485598963526399	bayes_pls_golite062009
pyrophosphatase activity	0.00282726023356339	bayes_pls_golite062009

No functions predicted.

Term	Confidence	Notes
oxysterol binding	5.62675037461468	bayes_pls_golite062009
sterol binding	4.18891468109664	bayes_pls_golite062009
	3.02967613614595	bayes_pls_golite062009
steroid binding	2.54679035876403	bayes_pls_golite062009
phosphoinositide binding	2.2725849852584	bayes_pls_golite062009
binding	2.10831141109811	bayes_pls_golite062009
phospholipid binding	2.08170907241909	bayes_pls_golite062009
lipid binding	1.8520231230392	bayes_pls_golite062009
cholesterol binding	0.644339278395346	bayes_pls_golite062009

No functions predicted.

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..180]	PSI-BLAST	31.0	Solution Structure of the Pleckstrin Homology Domain of Oxysterol-Binding Protein-Related Protein 8 (KIAA1451 Protein)
2	View Details	[181..248]	deduced	N/A	No confident structure predictions are available.
3	View Details	[249..605]	PSI-BLAST	75.0	Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
4	View Details	[606..733]	MSA	1.16098	View MSA. No confident structure predictions are available.

Protein Overview: obr-3

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: