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Protein Overview: nhx-8

General Information:
Name(s) found: nhx-8 / CE31093 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00003735 locus:nhx-8 Sodium\/hydrogen exchanger status:Confirmed UniProt:G5EFN1 protein_id:CAD36499.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 655 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article]
    regulation of pH [IEALink to PubMed article]
    Molecular Function: solute:hydrogen antiporter activity [IEALink to PubMed article]
    sodium:hydrogen antiporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFALKTALS ICIFLLIFQT VDSDSSDSSA SASVVSGAVK SEDTVVAVNK TDVLGEAIDA  60
   61 NATSLEQHGA AIVGNVSEEK KRSLAIFFIL FVIMLATLVV HMLIVSKIHW MPESLAIVAL 120
  121 GALIGSILSY SRRDWSEIEA LSPDVFFLVL LPPIIFENAY NLNKGYFFSN FVPILTFAIF 180
  181 GTTISAMVIG AGLYILGAIG LIFEFTFFEC FAFAAMISAV DPVGTLAIFQ AVKVESLLYM 240
  241 LVFGESMLND AVSIVLAATA LRHAKPSFNS LPASEIITSA FVTFTEMFFF SACLGVGIGL 300
  301 LSALLFKHVD LRKTPSLEFA LLLIFSYIPY GFAEALDLSG IMAILFCGIS MSQFTRHNVS 360
  361 PIAQITFRHT FRTISFVAET STFAYIGMAF FTIKLNFAPW LIFWSVVLCL LGRACNVFPL 420
  421 AYLVNQCRKD VQISMKNQII MWFSGMRGAV CFALVLYMDL DKEKKSILLT TVLFLILFTT 480
  481 IFLGGSALPF ISFINRCYPN ERQRKRRRTP RNKESTGNSS ALMMSKTQEM SFFGSDDWGP 540
  541 KKSALDATSS AGRIMRQLFV RKFTAIERLE NRDKLAALTK RALASDQMTD SDDVEFGGGG 600
  601 GVGGGGRMKD DVTPTRGRSG SRNSSDVIIS AGGGGVSGEH HLLISSGSDS STNEF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] MSA 1.976992 View MSA. No confident structure predictions are available.
    2 View Details [131..497] FFAS03 1.06 Crystal structure of the Na+/H+ antiporter NhaA
    3 View Details [498..655] MSA 1.679989 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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