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Protein Overview: lgc-40

General Information:
Name(s) found: lgc-40 / CE31248 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00020767 locus:lgc-40 status:Partially_confirmed UniProt:Q22741 protein_id:CCD71459.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 494 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: neurotransmitter receptor activity [IEALink to PubMed article]
    extracellular ligand-gated ion channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLHTMIRFL LSVCCIVNVF ESADLAFIPL TKAFLDKLKN ETLYNRFATP TQYDGVPTNV  60
   61 TLSMFIEGMS SFSAQTMDYH LDVYFQEEWY DHRLAHNASA PILVRDLTVF KMMWHPDVYF 120
  121 ANARSAAFQD ITDDNFLVWV YPNGRVWYDA RISIVSSCNM DLWKYPLDSQ ECALRILSYA 180
  181 YPMTVLRLLW SEKEDVPAID RNPDITMPDM SLKHIRTGYC NGTYATGEWS CMTAIFYVER 240
  241 EMMHHVMQTY VPTALIVVIS WFNFWLEIDS APARVSLSIT TLLTISTQAN AVKLALPEVS 300
  301 YMKAIDVWMG SCMAFVFGVM IEFTICHYAK NLEMLRGDGQ PSLIVDTALS TLFGAARDID 360
  361 DLVRKVATLN EEEGVRGDGE QHIALNMLNP EEPRLRSLNQ NNDVTANGTR YFVGAERMKR 420
  421 KRSKASLSRL RQQVASMRHA TIDVSRRAFN WTRALRNLRG RRVAQRIDER CRIVFPMIFL 480
  481 LFNVAYWSFY LVFN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..356] PSI-BLAST 68.221849 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    2 View Details [357..494] PSI-BLAST 35.045757 Acetylcholine receptor protein, beta chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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