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View Structure Prediction Details

Protein: lgc-40
Organism: Caenorhabditis elegans
Length: 494 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lgc-40.

Description E-value Query
Range
Subject
Range
gi|73974924 - gi|73974924|ref|XP_539232.2| PREDICTED: similar to cholinergic receptor, nicotinic, alpha polypeptid...
359.0 [0..27] [488..101]

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Predicted Domain #1
Region A:
Residues: [1-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLHTMIRFL LSVCCIVNVF ESADLAFIPL TKAFLDKLKN ETLYNRFATP TQYDGVPTNV  60
   61 TLSMFIEGMS SFSAQTMDYH LDVYFQEEWY DHRLAHNASA PILVRDLTVF KMMWHPDVYF 120
  121 ANARSAAFQD ITDDNFLVWV YPNGRVWYDA RISIVSSCNM DLWKYPLDSQ ECALRILSYA 180
  181 YPMTVLRLLW SEKEDVPAID RNPDITMPDM SLKHIRTGYC NGTYATGEWS CMTAIFYVER 240
  241 EMMHHVMQTY VPTALIVVIS WFNFWLEIDS APARVSLSIT TLLTISTQAN AVKLALPEVS 300
  301 YMKAIDVWMG SCMAFVFGVM IEFTICHYAK NLEMLRGDGQ PSLIVDTALS TLFGAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.221849
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [357-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDIDDLVRKV ATLNEEEGVR GDGEQHIALN MLNPEEPRLR SLNQNNDVTA NGTRYFVGAE  60
   61 RMKRKRSKAS LSRLRQQVAS MRHATIDVSR RAFNWTRALR NLRGRRVAQR IDERCRIVFP 120
  121 MIFLLFNVAY WSFYLVFN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.045757
Match: 1oedB
Description: Acetylcholine receptor protein, beta chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle