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Protein Overview: nhr-66

General Information:
Name(s) found: nhr-66 / CE31061 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00003656 locus:nhr-66 status:Confirmed UniProt:H2KYJ7 protein_id:CCD63562.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 577 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSGHVTTVD QQNRQQHQQQ QRQQQQAQQQ NSMARKYSMD TIQHHTMQHP HQLQYIPNHF  60
   61 MTASTDVFAA MDMSQKQSSP PGIFKIAKNE PSSSSNSQPG TPAMGDRRAV PACAICGTDS 120
  121 TGIHFGVDAC AACSAFFRRT VVLNKDYSCN KGGKCTVVKD GSAGQKCRAC RFRKCISSGM 180
  181 DKNSVQHRRD AIGKYSAGVK RELSPDAEFE PSAKVSTVSE PSTSSGPSGG FNQNVSSPAG 240
  241 IPRVPSTLRT TQASTCMNSA CGQKSVLHEL ICRQNFLTEQ RQLFYAGCLG DWFRKPSSIE 300
  301 NQTLSELTDF SSCMFHLWKI EPRLAADFMN RNRYLDPLPI VEKLKIYRNF VIMRQSVEEP 360
  361 YLTWRHGGLE KRWFVMPNNT YIDFNNIAKY FENGALKDLK LDYETTTNLF LPSFTHAMDT 420
  421 IGEKMKKNNI TETELTILLG LVLLDPGIYG IHESTRKFLK RIRDQLIHDV YMYYEDEMSH 480
  481 LYDPEIRMAD IFMLVAAIKI HSIKTSENMH MLRVFDLIPA DACFNQMLDV ESVNVSPDGQ 540
  541 KDSEAEQGPS PVSVPEAARG SYQDDDMPPV LEKNCDL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] MSA 4.539996 View MSA. No confident structure predictions are available.
    2 View Details [104..191] PSI-BLAST 26.30103 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
    3 View Details [192..577] PSI-BLAST 33.522879 hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle