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Protein Overview: yrs-1

General Information:
Name(s) found: yrs-1 / CE31714 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00006968 locus:yars-1 status:Confirmed UniProt:Q8MPU1 protein_id:CCD68725.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 327 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: tRNA aminoacylation for protein translation [IEALink to PubMed article]
    tyrosyl-tRNA aminoacylation [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    translation [IEALink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    tyrosine-tRNA ligase activity [IEALink to PubMed article]
    aminoacyl-tRNA ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHNSRKVTDQ ICKIFENAPG SSEKPIIVNN NDWLGKISLR DFLRECKNMQ VGKMLRMNTI  60
   61 KNRLEVGLSY TEFSYQTMQA FDWYTLSEKY GCRFQLGGYD QLGHLDFGAH YIKKMMNQAF 120
  121 AAGVCFPILT DSTGAKLGKS EGGGALWLDA TKTSPFHFYQ FFAQLHDDKA EELLLLFSLQ 180
  181 DIEHIRDVLK NHRSNLGQWI AQRELAAEIT RIVHGKEGLE VAMRCTKAMF GAKKADLSGL 240
  241 SRSEVLQLFR TTIDLKKENV ATMGQLADAS RLGSGKGHLL MQQGAFSVNG EKKRSPSESI 300
  301 ADVFLENASD LTLVCWGKRG YQLVRWV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..327] PSI-BLAST 85.30103 STRUCTURE OF TYROSYL-T/RNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.84668360172717 bayes_pls_golite062009
  • ligase activity
    		•  0.41353894226697 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  0.1911539125531 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  0.1911539125531 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  0.178548924377401 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle