Protein Overview: unc-53

General Information:
Name(s) found:	unc-53 / CE31346 [WormBase]
Description(s) found: Found 18 descriptions. SHOW ALL	WBGene00006788 locus:unc-53 Adapter protein unc-53 status:Confirmed UniProt:Q7YSI9 protein_id:CAD44132.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	1583 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	mating behavior [IMP] mesodermal cell migration [IGI] signal transduction [IPI] backward locomotion [IMP] oviposition [IMP] axon guidance [IMP] positive regulation of axon extension [IMP] actin cytoskeleton organization [ISS] positive regulation of multicellular organism growth [IMP] positive regulation of cell migration [IGI] determination of muscle attachment site [IMP]
Molecular Function:	actin filament binding [ISS] nucleotide binding [IEA][ISS] protein binding [IPI] nucleoside-triphosphatase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTSNVELIP IYTDWANRHL SKGSLSKSIR DISNDFRDYR LVSQLINVIV PINEFSPAFT  60
   61 KRLAKITSNL DGLETCLDYL KNLGLDCSKL TKTDIDSGNL GAVLQLLFLL STYKQKLRQL 120
  121 KKDQKKLEQL PTSIMPPAVS KLPSPRVATS ATASATNPNS NFPQMSTSRL QTPQSRISKI 180
  181 DSSKIGIKPK TSGLKPPSSS TTSSNNTNSF RPSSRSSGNN NVGSTISTSA KSLESSSTYS 240
  241 SISNLNRPTS QLQKPSRPQT QLVRVATTTK IGSSKLAAPK AVSTPKLASV KTIGAKQEPD 300
  301 NSGGGGGGML KLKLFSSKNP SSSSNSPQPT RKAAAVPQQQ TLSKIAAPVK SGLKPPTSKL 360
  361 GSATSMSKLC TPKVSYRKTD APIISQQDSK RCSKSSEEES GYAGFNSTSP TSSSTEGSLS 420
  421 MHSTSSKSST SDEKSPSSDD LTLNASIVTA IRQPIAATPV SPNIINKPVE EKPTLAVKGV 480
  481 KSTAKKDPPP AVPPRDTQPT IGVVSPIMAH KKLTNDPVIS EKPEPEKLQS MSIDTTDVPP 540
  541 LPPLKSVVPL KMTSIRQPPT YDVLLKQGKI TSPVKSFGYE QSSASEDSIV AHASAQVTPP 600
  601 TKTSGNHSLE RRMGKNKTSE SSGYTSDAGV AMCAKMREKL KEYDDMTRRA QNGYPDNFED 660
  661 SSSLSSGISD NNELDDISTD DLSGVDMATV ASKHSDYSHF VRHPTSSSSK PRVPSRSSTS 720
  721 VDSRSRAEQE NVYKLLSQCR TSQRGAAATS TFGQHSLRSP GYSSYSPHLS VSADKDTMSM 780
  781 HSQTSRRPSS QKPSYSGQFH SLDRKCHLQE FTSTEHRMAA LLSPRRVPNS MSKYDSSGSY 840
  841 SARSRGGSST GIYGETFQLH RLSDEKSPAH SAKSEMGSQL SLASTTAYGS LNEKYEHAIR 900
  901 DMARDLECYK NTVDSLTKKQ ENYGALFDLF EQKLRKLTQH IDRSNLKPEE AIRFRQDIAH 960
  961 LRDISNHLAS NSAHANEGAG ELLRQPSLES VASHRSSMSS SSKSSKQEKI SLSSFGKNKK1020
 1021 SWIRSSLSKF TKKKNKNYDE AHMPSISGSQ GTLDNIDVIE LKQELKERDS ALYEVRLDNL1080
 1081 DRAREVDVLR ETVNKLKTEN KQLKKEVDKL TNGPATRASS RASIPVIYDD EHVYDAACSS1140
 1141 TSASQSSKRS SGCNSIKVTV NVDIAGEISS IVNPDKEIIV GYLAMPTSQS CWKDIDVSIL1200
 1201 GLFEVYLSRI DVEHQLGIDA RDSILGYQIG ELRRVIGDST TMITSHPTDI LTSSTTIRMF1260
 1261 MHGAAQSRVD SLVLDMLLPK QMILQLVKSI LTERRLVLAG ATGIGKSKLA KTLAAYVSIR1320
 1321 TNQSEDSIVN ISIPENNKEE LLQVERRLEK ILRSKESCIV ILDNIPKNRI AFVVSVFANV1380
 1381 PLQNNEGPFV VCTVNRYQIP ELQIHHNFKM SVMSNRLEGF ILRYLRRRAV EDEYRLTVQM1440
 1441 PSELFKIIDF FPIALQAVNN FIEKTNSVDV TVGPRACLNC PLTVDGSREW FIRLWNENFI1500
 1501 PYLERVARDG KKTFGRCTSF EDPTDIVSEK WPWFDGENPE NVLKRLQLQD LVPSPANSSR1560
 1561 QHFNPLESLI QLHATKHQTI DNI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: unc-53

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: