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Protein Overview: mec-2

General Information:
Name(s) found: mec-2 / CE30952 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00003166 locus:mec-2 status:Confirmed UniProt:Q8MQ74 protein_id:CCD83469.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 392 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    neuron projection [IDALink to PubMed article]
    Biological Process: mechanosensory behavior [IMPLink to PubMed article]
    response to mechanical stimulus [IMPLink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]
    peptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATMSSARN SVVSLSSNGS VKVETRLVSN ERSSSIQQEG AMLPSSSSKD DDLLSTSSDE  60
   61 VENMATRTLQ QLEESTSIIS ANSDDDSVKK EKQAEKDVEK GNGKEEKANI QNEFGVCGWI 120
  121 LTILSYLLIF FTLPISACMC IKVVQEYERA VIFRLGRLMP GGAKGPGIFF IVPCIDTYRK 180
  181 VDLRVLSFEV PPQEILSKDS VTVAVDAVVY FRISNATISV TNVEDAARST KLLAQTTLRN 240
  241 ILGTKTLAEM LSDREAISHQ MQTTLDEATE PWGVKVERVE VKDVRLPVQL QRAMAAEAEA 300
  301 AREARAKVIV AEGEQKASRA LKEAAEVIAE SPSALQLRYL QTLNSISAEK NSTIIFPFPI 360
  361 DLLSAFLQRT PPKVDNNFAF PTHKAGGIPS SS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144] MSA 1.664975 View MSA. No confident structure predictions are available.
    2 View Details [145..326] PSI-BLAST 12.39794 Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
    3 View Details [327..392] MSA 2.678995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.67282155252301 bayes_pls_golite062009
  • structural molecule activity
    		•  0.834496144484266 bayes_pls_golite062009
  • protein binding
    		•  0.769979871341236 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle