Protein Overview: unc-44

General Information:
Name(s) found:	unc-44 / CE31847 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006780 locus:unc-44 status:Partially_confirmed UniProt:Q17490 protein_id:CCD61798.1 [WormBase] gi\|71981411\|ref\|NP_001021268.1\| UNCoordinated family member (unc-44) [Caenorhabditis elegans] [NCBI NR] gi\|23820861\|gb\|AAA93447.2\| Uncoordinated protein 44, isoform f [Caenorhabditis elegans] [NCBI NR] [wormpep88.fasta] Uncoordinated protein 44, isoform f [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] CE31847 WBGene00006780 locus:unc-44 AO13 ankyrin status:Partially_confirmed TR:Q17490 protein_id:AAA93447.2 [wormpep150.fasta] 31847 WBGene00006780 locus:unc-44 AO13 ankyrin status:Partially_confirmed TR:Q17490 protein_id:AAA93447.2 [wormpep130-phg-ecoli-orf-rand.fasta] locus:unc-44 AO13 ankyrin status:Partially_confirmed TR:Q17490 protein_id:AAA93447.2 [wormpep115.fasta.reversed] CE31847 WBGene00006780 locus:unc-44 AO13 ankyrin status:Partially_confirmed UniProt:Q17490_CAEEL protein_id:AAA93447.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE31847 WBGene00006780 locus:unc-44 AO13 ankyrin status:Partially_confirmed UniProt:Q17490_CAEEL protein_id:AAA93447.2\| [wormORF-contam.fasta] UNCoordinated family member (unc-44) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE31847 WBGene00006780 locus:unc-44 AO13 ankyrin status:Partially_confirmed UniProt:Q17490 protein_id:AAA93447.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE31847 WBGene00006780 locus:unc-44 AO13 ankyrin status:Partially_confirmed UniProt:Q17490 protein_id:CCD61798.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE31847 WBGene00006780 locus:unc-44 status:Partially_confirmed UniProt:Q17490 protein_id:CCD61798.1 [wormpep246-ecoli-contam.fasta] Uncharacterized protein OS=Caenorhabditis elegans GN=unc-44 PE=1 SV=2 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	6994 amino acids
Gene Ontology:
Cellular Component:	lateral plasma membrane [IDA] proteinaceous extracellular matrix [IEA]
Biological Process:	carbohydrate metabolic process [IEA] locomotory behavior [IMP] signal transduction [IEA] positive regulation of growth rate [IMP] cell adhesion [IEA] blood coagulation [IEA] positive regulation of multicellular organism growth [IMP] positive regulation of locomotion [IMP]
Molecular Function:	protein binding [IEA] hydrolase activity, hydrolyzing O-glycosyl compounds [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNEGDPPQP QQQQPESQEV QAPAAPEPGR AEGSASFLRA ARAGDLEKVL ELLRAGTDIN  60
   61 TSNANGLNSL HLASKEGHSE VVRELIKRQA QVDAATRKGN TALHIASLAG QSLIVTILVE 120
  121 NGANVNVQSV NGFTPLYMAA QENHEEVVKY LLKHGANQAL STEDGFTPLA VALQQGHDRV 180
  181 VAVLLENDSK GKVRLPALHI AAKKDDTTAA TLLLQNEHNP DVTSKSGFTP LHIAAHYGHE 240
  241 NVGQLLLEKG ANVNYQARHN ISPLHVATKW GRTNMANLLL SRGAIIDSRT KDLLTPLHCA 300
  301 ARSGHDQVVD LLVVQGAPIS AKTKNGLAPL HMAAQGDHVD AARTLLYHRA PVDDVTVDYL 360
  361 TPLHVAAHCG HVRVAKLLLD RSADPNSRAL NGFTPLHIAC KKNRIKVVEL LLKYRAAIEA 420
  421 TTESGLTPLH VAAFMGAINI VIYLLQQGAN PDVETVRGET PLHLAARANQ TDVVRVLIRN 480
  481 GAKVDAQARE LQTPLHIASR LGNTDIVILL LQAGANSNAT TRDNYSPLHI AAKEGQEEVA 540
  541 GILLDHNADK TLLTKKGFTP LHLASKYGNL EVVRLLLERG TPVDIEGKNQ VTPLHVAAHY 600
  601 NNDKVAMLLL ENGASAKAAA KNGYTPLHIA AKKNQMEIAS TLLQFKADPN AKSRAGFTPL 660
  661 HLSAQEGHKE ISGLLIENGS DVGAKANNGL TAMHLCAQED HVPVAQILYN NGAEINSKTN 720
  721 AGYTPLHVAC HFGQLNMVKF LVENGADVGE KTRASYTPLH QAAQQGHNNC VRYLLENGAS 780
  781 PNEQTATGQT PLSIAQRLGY VSVVETLRTV TETTVITETT TVDERYKPQN PEAMNETMFS 840
  841 ESEDEGQAAE HEAVAAHEKD FSDNLTQGLQ DSTGVHMIHT GEQLLQRSQE LENGGAIPKI 900
  901 NSGGMSPEKE FAKIAPVATS SPIATSNSQS FGIAPRAGSI SGQFQQQPLH GAGPEDNLEE 960
  961 LVRRAQNHPI NAGNYDNGGV AMLENGHADN VPIGHHVTQP SKLQHRTFLI SFLVDARGGA1020
 1021 MRGCRHSGVR IIVPPRKASQ PIRVTCRYLR KDKLAHPPPL SEGEELASRI LEMAPAGAKF1080
 1081 LGPVILEVPH FASLRDRERE IVILRSDDGQ HWKEHQLEAT EDAVQEVLNE SFDAEDLAQL1140
 1141 DDLQTPRITR ILTSDFPMYF AVVTRVRQEV HCVGPEGGVI ISSVVPRVQA IFPDGSLTKT1200
 1201 IKVSVQAQPV PQEMVTRLHG NRVAVSPIVT VEPRRRKFHK PITLCIPLPQ SNNRGMLTQY1260
 1261 SGQQGQEPPT LRLLCSITGG SAPAQWEDIT GTTQLTFTGD EVSFTTTVSA RFWLMDCQTP1320
 1321 RDAARMAQEV YNEAISIPYM AKFAVFARRT FPVEGQLRVF CMTDDKEDKT LEKQEHFKLI1380
 1381 AKSRDVEVLK GKHQFLEFSG NLVPITKSGD QLSLFFLPFQ ENRLAFMVKT RSNDDNEAAT1440
 1441 EGRIGFMAEP KIRSDALPPQ QPICTLAISL PEYTGEIKTA PPPKKDLTPF EQRYGSALEK1500
 1501 DLPEFVHQNV LKGIGADWPR LGRALEVPHR DIQHIRQNYP GQECKNTLKI WIHLKKEDAN1560
 1561 QDNLDQALRQ IGRDDIVRSI AYGEPDALIN YSQADSPSQK REPIRHFEEV PAATLVKREV1620
 1621 RTEDLVTREP VQPTHHVEQA TTVVQEPSYS APVHHSPVPE EPEMEEEAPV AEMRTVVRTE1680
 1681 RHVHDSEDGP VVEERTITTT YEDDVAVNEN IVDRTVPLNE DEQQKWEELN RLADESSPSP1740
 1741 AQRSTIVAES TSEQVPEDVE QSVESESHRE DDGTIVTTTV TTSHISESPS GSPTRRSVEP1800
 1801 EEHRHSQHED HEASGAEQHS GQDSGTTQKK ETAEEGFTNE DGSVVVSKKM TRVVTTTRTT1860
 1861 LPGEGEEPSA PDSPVESLGS VKDRIAKFEQ FKTLPIDPSV SGPPPSAHTL QSEEYQEESG1920
 1921 NVESAYDVET DRRDSERSLK SERSIPEIHT SPSEEQQSEH FESAEHTEDQ GRDSGRSLKS1980
 1981 DRSIPEVQFT ESDSELEKHD LHEDSHLEPT VGIVITPHTP VPPEHPDDKE DIEDEQPQEP2040
 2041 LEPSEPEHVA HAELKDTREY SDEELAQELS PSEEHVSTAE IKDIKSYSPT SSDDERSSQK2100
 2101 GKVSPPIPQV RHAISPSVAS EVLSSHDDEL AAHFVAESFE KHDEGNVETI EQTPVYKGHH2160
 2161 SPGQTSPIVS EHPHAQEYAE SVTSHDEGDN LSLKSGHEPE IARHSVASVQ EEDDDDDEKS2220
 2221 ELGDFAKKAG MIVGGVIAAP VALAAVGAKA AYDALNRDDD EEKLEGHEEK EVLTTQTTIM2280
 2281 ESPIRHEDIP SPHLEDVTPK VSHQEHPYEH VTETTTTVTR DYYEQPEDHR EASPAPSSHV2340
 2341 ESERPISESP AVSEREPSHI ATETTTTVTR EYDQEPKADQ SSARESVRDL VSEEHEHPAC2400
 2401 DSERLSEPAQ SPEPVETHAE SQFSNLVETT TTTAVTREFY DEDQEEQASS RATKERIEQS2460
 2461 PVASERSIVS TEHRQSPTQE SEQSLEPTSE KNVHTVTETT TVTRECFEEP IASELEHASR2520
 2521 EFEQGSNDFR RSVSPVDAQE QVDVPHSPAP SSHAESEQPV PESPHHIVET TTTTTVTREF2580
 2581 QDEEYPRPES PAEIFPIPSS EQQSEEPHIV KETTTTTTVT RELYDEPEKG NVTFSPAPSS2640
 2641 HAESERQVPE SPVVSHQEYP HVVETTTTTN VTSNIYDDED NVPSSEDPAT QHFQQSETSV2700
 2701 HRSHPDSVEE SDGEGLGSKV LGFAKKAGMV AGGVVAAPVA LAAVGAKAAY DAFEKDDEDD2760
 2761 ETSHSPESPV PEYQSEQYQD DSAQSSHTDF EHHMPESPIE HEKETEEFDH SHPESPVLSE2820
 2821 KEREHQVTSE TTTTTTVTRE YNDEPEDEQE HQGPHSPAPS SHTEAEHPHI VETTTTTTVT2880
 2881 REFQEEPEEL EYKQEDNSRK SPSSHSQENL VTETTTTTTV TSEYYDEPEH FEEQETGKSS2940
 2941 PAPSSHVESE RQVLESPVAS DPRHVMETTT TTTVTRQFHD DESERSDSPN RDVVEAQSIH3000
 3001 SSNIESHQQF SEKDDDSQRG PSPVKSEDEP VKHESYKFET STTETREFDR PELDSERLSE3060
 3061 PAQSPMEVSP ITTEENIVRP SSSVKSEYGS EGHVPSVIET KTTTTVTREF YDDDQDEHEN3120
 3121 QTQSEELRSS IPTEEEEHEG SHLFKETTTT TTVTREFYDE PENVEELQDP QFSPAPSSHV3180
 3181 ESGIHASESP VAQQQEIPQT REFHEDSPAA QYFHEEEYES HVLTEQAPLL TEQQHQPESG3240
 3241 DESDGEGLGS KVLGFAKKAG MVAGGVVAAP VALAAVGAKA AYDALKKDDD EEDQEERESL3300
 3301 LRQERSIDSP HASEQSQIEE EHERFEESPV PSEKHHVTET TTTTTVTREY FDEHEPLVSQ3360
 3361 EIEGEKGSPA DSEKSLPHVV ETTTTTTVTR EFDKNDSESP VPSEKEQEPT TVSREVYETA3420
 3421 EGDEPEHHYT ETTTTTVTKE VIDDSQEMGD DDEPKQESPQ VVETTTTTMT SREYDDNDDE3480
 3481 TRSEAGDSHI TETTKTTTVV REFHGEQPEE TEETDEVEEL PPKIEEEDNV SEYSESSTSV3540
 3541 SREVRPDEPH IIETTTTTTV TREYHNEPEE TYDDQKDAAP ISFSQEHQDD DSQASHDQHD3600
 3601 RESPVESEKS VKHTTETTTT TTVTRQLYDD EASEIRGESP VATEEHEHVS STKSDDESEQ3660
 3661 HVPSVIETTT TTTVTREFYD DQDELQREDH TQSEERRSSI PTEETEHEDS HLIKETTTTT3720
 3721 TVTREFYDEP ENVEKLQDSQ FSLSPSSHVE SEIYVPESPV AKQQEIPQTR EFHEDSPAAQ3780
 3781 YFHEDEYEHQ VPTEQAPLLT EQQHQPESGE ESDGEGFGSK VLGFAKKAGM VAGGVVAAPV3840
 3841 ALAAVGAKAA YDALKKEDDE EDQEERESLI REERSFDSPH ASEQSQIEKE HKRFEESPVP3900
 3901 SEKHHDQSSA LPQESVSQPI EKESRTFNDE SEFGVKSDHY TEDDQESLKS PKESGEAFSQ3960
 3961 FTSEKEQDRS DSPIHSQKED ISQFQNESSP EDVKSEQPHD EEKPDLERQG SYSSGYSPKS4020
 4021 PGGSITGLDE EKALSGVQEP EDRPENFAES HEKTEATSDE NLFESDKYAP ASPVPSEDSS4080
 4081 NRVIETTTTT TVTREHFEPE DDHSYVVESQ EYSSSGSPVP SEKSVDRVIE TTTTTTVTRE4140
 4141 HFEAEDEIPT IVESSHDDQA ASPVPSEEDV HEQIQTTTTT TTVTKEHFVP DDEIDSEHMN4200
 4201 ESDKYASGSP VPSEEDSSRV TETTTTTTVT REHFEPEDDH SPVVQTQEYS ASESPVPSEK4260
 4261 SVERVIETTT TTTVTREHFE DEDHILGQQG ESDSQIPSES ITSENMDRET SSSPVQSNRD4320
 4321 EEFVLPAIAP YKQPTEYGRV DSHDAPASPA PSAESPIQAY KQEESQEAHS LEQFQQRSSV4380
 4381 SHEDSPAAQY FHDNESDHDS PVPSDRAPLL TEQQHQPESG EESDGEGFGS KVLGFAKKAG4440
 4441 MVAGGVVAAP VALAAVGAKA AYDALKKDDD EDENPDEQEK LLPKSPERQV LVNPVEPSDS4500
 4501 EISEIELEYT SPSPTEKSES QCYTETVRTT TVTREYLDDP QSVTRSRSPS EHDISEQYAP4560
 4561 ESPVEQDPYV VEKTTTVIRQ YHDEPPQEIE EQTIPEEVTV LREVYESPEG DEPEQHYIET4620
 4621 KTTTTITKEV HVPVEEDVQI SPVHSETSVS EKQLPADEQL DEPVTESTTT ATVTRERYEE4680
 4681 PEEVRPPSGS EADDESHAPK YMETTTTTTV TREYEVSEDE DEHQQSQVQR DESPAPSEDS4740
 4741 VKHVIEKTTT TTVTEERYEP EDSHSPVPSE DDVHGFVKTT TTTTTVTHEH FEPEDPPSDE4800
 4801 HVVESERYAS GSPVPSEEDS SREIETTTTT TVTREHFELE DDQEHVVESQ EYSASGSPVP4860
 4861 SEKSVERVIE TTTTNTVTRE HFEHEDDIPT IVETSHDDPA ASSVPSEEDV HGQIQTTTTT4920
 4921 TTVTREHVVP DEEIDSGRMD ELEKYSSESP VPSEEDSSRV IETTTTTTVS REHFEPEDDH4980
 4981 SHVVESQEYS ASGSPVPSEK SVERVIETTT TTTVTREHFD TEEDYIPSES RTSHDDGITD5040
 5041 QHVPSQSPVP SEEDDHVTHE QIIRDDPIDE QIVESHEYKS ESSIPSEQDS THVIETVMST5100
 5101 PITSERYDPE VEKDVVESAD DEIDSSTAQY YKSESPVQTE KSLLLAKQQQ ESGDESDGEG5160
 5161 FGSKVLGFAK KAGMVAGGVV AAPVALAAVG AKAAYDALKK DDDEEDQEDK EPLIGGFHKD5220
 5221 QDPISQDEPS AVDSETQEPG ATFYEPEEED KVITDSADSS VVQDEPKIVF PVDSTPEHHS5280
 5281 NDREEFESIV KSEGPYIVES TDYAQTSAEE PRISSPVHSD AGDASSFKRP ESVTGEDEKN5340
 5341 AIPETSETDA PYVIDSEEYE FNNRDEQRIS SPAHSDEEDE NDAEVIDSEF YRHSQEQNNE5400
 5401 EDPSIVESGE YISSGHGSPR PFEDSTTTTV LNVHHEPAAI PEPEVDEEEL EQERSIIESE5460
 5461 EYKTSSPLPP TSVTTVEHVE PAEIHKYRTT SPTIVTTVSS EHLDRNQEPY VVESEEYTRA5520
 5521 SPLGPERPES PSGSPLPREE DDSHVIESHE YTSSPVPSED SVKHVIEKTT TTTVTEERYE5580
 5581 PEDSHSPVPS EDDVHGFVKT TTTTTTVTHE HFEPEDHTSD EHVVESERYA SGSPVPSEEN5640
 5641 SNRVTETTTT TTVTREHFEP EDDQEHVVES QEYSASGSPV PSEKSVEKVI ETTTTTTVTR5700
 5701 EHFEHEDEIP TIVESSHDDQ AASSVPSEED VHGQIQTTTT TTTVTREHVV PDEEIDSGRM5760
 5761 DELEKYSSES PVPPEEDSSR VIETTTTTTF IREHFEPEDD HSHVVGSQEY SASGSPVPSE5820
 5821 KSVERVIETT TTTTVTSEHF EHEDEHAQLH DTVSSEKTSS SEPVEQTLEE ADITEETHQR5880
 5881 FSAEDEHQPT STEKPVHGFM ETTSTSHTAS HVELEHRDDD DESGGEGFGS KVLGFAKKAG5940
 5941 MVAGGVVAAP VALAAVGAKA AYDALKKDDD EEATYDLDRE HGSYESAELQ RPTQQVESRQ6000
 6001 EDSESEGSFV DHGEDSQHLP VQSTEAAFKL SSEDIAEQTA EKLVSEVFAP LDRTLIESEQ6060
 6061 YRASIESLNR RSPVEPKRSV EDLASEALQN VTKISFGHAD ESDDKHDGDN DGEWKVYDRH6120
 6121 GEVLEEFSTQ LTDDVIQEAE GDATTHIMMT QAEYSPRRSK FLKQESCQEI SNEPEVDYYS6180
 6181 DLQEKLNILA GEKNNLHALV EEEPSSSASD QLDVIHESDQ EAHLEQEHQQ EAAAQKEQDE6240
 6241 KEEAAEYTAT LLVDDVLQQV VQEINEEDDD KKTMTSTSYL TATEKDDQEY DTCVTSQDDT6300
 6301 YESAQGWTSQ DSEYTTATSQ APSRLSDSDA ELTARDHDQE RQETSTPQAI LSPVDSDRHF6360
 6361 TVQQDFEMPV IRAFDPDDFM QTTARSTPDV ALQVTIEEED ESDDKLPISP SGILLPPKHD6420
 6421 PGRPISPVPP RKSDGTMQKE GDHFVFVREE DTIAEPTPPP QPAEPEQLAE YEATKESEHQ6480
 6481 QITEGDVPQE EEETEMRRQE TERIHSLAME ASSDLGNSES SRYSRQLSDL SSSAESHADT6540
 6541 VIRVESERSG SSDSLEVVSV ISAGKDAQMS EKSLTPEDPE KPTDSVQEHQ QKDQEQAEAE6600
 6601 DQREAEDLGF EVYDADTEEQ NQQLEELETV EEEPEDSDSL NEGGNHSSGH SSVGVPADTL6660
 6661 AMIGKYRHQS SDNLSLTSLQ EFERLEKEVG ARGDGSLTRS EIELLVAGRL NKSGEGSVSS6720
 6721 LAEFERLEKE MTENQSPPED VMMLSDIREE SEAEDMSIRD DDEEDAEGSD TELKSRPVQE6780
 6781 EDLRVITPIA PSPTDSLDHA VDAVQMQYLE TSTDSLEPTF QEIEVEQRPE SVEDTSLTEY6840
 6841 EVIPRVMEAS TTDSLDGTAT IEKDSVLEGA SQGIESTQST HGLLSGDTMG TVVTDDDRDS6900
 6901 LDGEMSSMLQ SYPTTLTTFQ TTVVGPDGSL QTISRRVETK VTDPLVSHVT FTGTESQERL6960
 6961 DQLPDDEQFE TVDTEGNVTR TTFHREHDQQ QPHF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: unc-44

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: