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Protein Overview: hlh-1

General Information:
Name(s) found: hlh-1 / CE31766 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00001948 locus:hlh-1 Myoblast determination protein 1 homolog status:Partially_confirmed UniProt:P22980 protein_id:CCD61731.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 320 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    Biological Process: muscle organ development [ISSLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    protein heterooligomerization [ISSLink to PubMed article]
    regulation of transcription [IEALink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [ISSLink to PubMed article]
    Molecular Function: transcription regulator activity [IEALink to PubMed article]
    RNA polymerase II transcription factor activity, enhancer binding [ISSLink to PubMed article]
    bHLH transcription factor binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTETSTQSA PSDTYDTSIY YNSSPRVTAN DITTLTSFAA PAPQVLDYAN TQYDIYRNQP  60
   61 AYYLPSYAPT APTTFYSDFA NFNVTRSQDF ASVPAVANSS DVKPIIIKQE KSTPNATELI 120
  121 IQSRVDSQHE DTTTSTAGGA GVGGPRRTKL DRRKAATMRE RRRLRKVNEA FEVVKQRTCP 180
  181 NPNQRLPKVE ILRSAIDYIN NLERMLQQAG KMTKIMEQNQ HLQMTQQING APPHDYVTSS 240
  241 HFASSSYNPE NMFDDDDLTD SDDDRDHHKL GNAVDLRRRN SLDRLSRIVA SIPNEEAMTD 300
  301 EQLLQPANDV IDGEKKLEML

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..131] MSA 15.268995 View MSA. No confident structure predictions are available.
    2 View Details [132..225] PSI-BLAST 16.39794 Myod B/HLH domain
    3 View Details [226..320] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.28018660287528 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.87754990073909 bayes_pls_golite062009
  • DNA binding
    		•  1.73664400879211 bayes_pls_golite062009
  • transcription factor activity
    		•  1.6095946900662 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.57122223638621 bayes_pls_golite062009
  • protein binding
    		•  0.78099405089238 bayes_pls_golite062009
  • transcription activator activity
    		•  0.314165294474 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle