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Protein Overview: CE29830

General Information:
Name(s) found: CE29830 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00012316 locus:ctps-1 CTP synthase status:Partially_confirmed UniProt:G5EC98 protein_id:CAA16517.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 672 amino acids

    Gene Ontology:
    Cellular Component: ribosome [IEALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    pyrimidine nucleotide biosynthetic process [IEALink to PubMed article]
    GMP biosynthetic process [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    translation [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    structural constituent of ribosome [IEALink to PubMed article]
    GMP synthase (glutamine-hydrolyzing) activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    CTP synthase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGEKRVKYI LVTGGVISGV GKGIISSSLG VLLKNNGYKV SAIKIDPYLN EDAGTFSPYE  60
   61 HGEVFVLDDG GEVDLDLGNY ERFLDIRLTR DNNITTGKMF KHVMERERRG DYCGKTVQMI 120
  121 PHLTDAIVDW IERVARIPVD GTSEQPDVCI IELGGTIGDI EGMTYLSAFE RFQRPTLKND 180
  181 LMNVHVSLIL HPNATGEPKT KPMQNSVRHL RAAGLVPDLL ICRSTEKLDP HLREKIAGFG 240
  241 MMDLEQVVGV HDVSNIYKVP LLLQQQGVLE AITQRLRLSE ISENIRKDLK FNMNHWTNLS 300
  301 ELCDTFQQVV NIALVGKYVK IADAYASVNK ALSHAAIHAK RKLKITYVDS ELLENKPGME 360
  361 EQSRAAWDSV KAADGVIVPG GFDKRGVEGM INAAEYCRKN DVPYLGVCLG MQVAAIEFAR 420
  421 NVLSIDGANS TEFNSKLHEN QQIVIDMPEH NVEEKGLGGT MRLGRRSTVF LTDECILHRL 480
  481 YGTHTVEERH RHRYEVNPHV VPQMARKGFL FVGMGVDEQN TDIWDVKKRT DSSAELMQMA 540
  541 DQTEIDLLHK IDDLCQRGGD GVTRPAVRME MFEMKDHPYF VGAQFHPEYL SHPLTPSPPF 600
  601 FGLLLAATRQ LNSYFSGSRS PALQVVNEEE HLHHTKENDS EEKREDVVGA MLGKLKLEGN 660
  661 AVPGTQRLAS FH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..672] PSI-BLAST 1000.0 Crystal Structure of T.th. HB8 CTP synthetase complex with Glutamine

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  3.31067140196309 bayes_pls_golite062009
  • carbamoyl-phosphate synthase activity
    		•  3.20040964426687 bayes_pls_golite062009
  • carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
    		•  3.1924950908778 bayes_pls_golite062009
  • carbon-nitrogen ligase activity, with glutamine as amido-N-donor
    		•  2.70451256281397 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.38022153735887 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.22928921532687 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.90285342513072 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.8179707949172 bayes_pls_golite062009
  • binding
    		•  1.80700250246233 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.58983962677151 bayes_pls_golite062009
  • phosphoribosylformylglycinamidine synthase activity
    		•  1.51568729563523 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  1.50403004795816 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.38266739305428 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • CTP synthase activity
    		•  0.554689818807922 bayes_pls_golite062009
  • anthranilate synthase activity
    		•  0.243205818526006 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.216266069700019 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  0.12351419478929 bayes_pls_golite062009
  • protein binding
    		•  0.071010918255742 bayes_pls_golite062009
  • nucleotide binding
    		•  0.0593371872166591 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.45

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle