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Protein Overview: hgo-1

General Information:
Name(s) found: hgo-1 / CE29602 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00001843 locus:hgo-1 Homogentisate 1,2-dioxygenase status:Confirmed UniProt:Q9Y041 protein_id:CAA22255.4 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 437 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: L-phenylalanine catabolic process [IEALink to PubMed article]
    tyrosine metabolic process [IEALink to PubMed article]
    Molecular Function: homogentisate 1,2-dioxygenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEFDELKYL TGFGNEHATS DPRVPDALPV GQNSPQKCSH GLYAEQLSGT AFTAPRSQNQ  60
   61 RSWLYRIRPS VIHRPFEAMK ENDQHWTNNF SSIPPNPNQY RWNPFPLPTK EGVTFVDNLY 120
  121 TVCGGGDVIS RTGLAIHQFS CNASMEHTAM YNSDGDFLIV PQQGALEITT EFGRLLVNPQ 180
  181 EIAVIPQGIR FSVAVRGPSR GYILEVYGTH FQLPDLGPIG ANGLANPRDF EAPVAWFEDL 240
  241 DVEFTIINKY QGSWFQAKQG HSPFDVVGWH GNYVPYKYDL KKFMVINTVS FDHCDPSIFT 300
  301 VLTAPSVKHG TAIADFVIFP PRWGCADNTF RPPYYHRNCM SEYMGLITGC YEAKEGGFKP 360
  361 GGGSLHSMMT PHGPDFNCFE MASNADLKPQ RVAEGTMSFM FESSLNMAIT NWAVYQNVDK 420
  421 DYYKDWQPLK KHFTMPK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..437] PSI-BLAST 1000.0 Homogentisate dioxygenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
    		•  2.65960759413149 bayes_pls_golite062009
  • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
    		•  2.611114803333 bayes_pls_golite062009
  • homogentisate 1,2-dioxygenase activity
    		•  2.36574960723119 bayes_pls_golite062009
  • dioxygenase activity
    		•  0.930778069601015 bayes_pls_golite062009
  • catalytic activity
    		•  0.401988496917198 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle