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Catalysis of the reaction: homogentisate + O2 = 4-maleylacetoacetate. Catalysis of the incorporation of both atoms of oxygen from one molecule of O2 into the (reduced) substrate. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: homogentisate 1,2-dioxygenase activity
Acc: GO:0004411
Aspect: Molecular Function
Desc: Catalysis of the reaction: homogentisate + O2 = 4-maleylacetoacetate.
Synonyms:
  • homogentisic oxygenase activity
  • homogentisic acid oxygenase activity
  • homogentisate dioxygenase activity
  • homogentisicase activity
  • homogentisate oxidase activity
  • homogentisate:oxygen 1,2-oxidoreductase (decyclizing)
  • homogentisic acid oxidase activity
  • homogentisate oxygenase activity
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004411 - homogentisate 1,2-dioxygenase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle