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View Structure Prediction Details

Protein: hgo-1
Organism: Caenorhabditis elegans
Length: 437 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hgo-1.

Description E-value Query
Range
Subject
Range
gi|68404243 - gi|68404243|ref|XP_684657.1| PREDICTED: similar to Hgd protein isoform 1 [Danio rerio]
709.0 [0..7] [436..4]

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Predicted Domain #1
Region A:
Residues: [1-437]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEFDELKYL TGFGNEHATS DPRVPDALPV GQNSPQKCSH GLYAEQLSGT AFTAPRSQNQ  60
   61 RSWLYRIRPS VIHRPFEAMK ENDQHWTNNF SSIPPNPNQY RWNPFPLPTK EGVTFVDNLY 120
  121 TVCGGGDVIS RTGLAIHQFS CNASMEHTAM YNSDGDFLIV PQQGALEITT EFGRLLVNPQ 180
  181 EIAVIPQGIR FSVAVRGPSR GYILEVYGTH FQLPDLGPIG ANGLANPRDF EAPVAWFEDL 240
  241 DVEFTIINKY QGSWFQAKQG HSPFDVVGWH GNYVPYKYDL KKFMVINTVS FDHCDPSIFT 300
  301 VLTAPSVKHG TAIADFVIFP PRWGCADNTF RPPYYHRNCM SEYMGLITGC YEAKEGGFKP 360
  361 GGGSLHSMMT PHGPDFNCFE MASNADLKPQ RVAEGTMSFM FESSLNMAIT NWAVYQNVDK 420
  421 DYYKDWQPLK KHFTMPK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1ey2A
Description: Homogentisate dioxygenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2.65960759413149 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2.611114803333 bayes_pls_golite062009
homogentisate 1,2-dioxygenase activity 2.36574960723119 bayes_pls_golite062009
dioxygenase activity 0.930778069601015 bayes_pls_golite062009
catalytic activity 0.401988496917198 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle