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Protein Overview: kap-1

General Information:
Name(s) found: kap-1 / CE30650 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00002182 locus:kap-1 status:Confirmed UniProt:H2KZP1 protein_id:CCD69059.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 696 amino acids

    Gene Ontology:
    Cellular Component: kinesin complex [IEALink to PubMed article]
    Biological Process: microtubule-based movement [IDA]
    Molecular Function: kinesin binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQVSIDAHP SDQAIIVRFE QSPTNVESLG HQKIIHLKEM SLDVDIRALS NVILQKCLFI  60
   61 PATSRSQLEQ VLFYIQKRGN QRISARSRSS SAVSFDRRPI HSPTISAELG KIDEYIECFY 120
  121 GETSVEKNKG AVALYELSKN PQNLTQLVNN ETLMMALARV FREDWKKHFE VGTNIMNLFV 180
  181 NISKFSCLHG ILLHHKIGTL CVNAMEHETK RYDFWIAEMK KTDQETLRKL KTAIRKQAML 240
  241 LAACVTFLTN LATDISVELK MVRRNLVALL VKCLQMSSES TSSLTTATIK FLLKLSIFDE 300
  301 NKIVMEQNGT IEKLLKLFPI QDPELRKAVI MLLFNFSFDS KNLPKMVNGG LVPHMASLLD 360
  361 SDTKALNMMY LLSCNDDAKA MLAYTDAIKL LMKDVLSGTG SEVTKAVLLN ICLEKRNAQL 420
  421 VCGQRGQGLD LLMEMSINSR DLMLIKVVRA ISSHEGATQN MFLKWIETLI GIAKNEGADN 480
  481 SESKSSFGLE CMGTVAELKV APWAKIIQSE NLVPWMKTQL QEGIDESEEV TVLRDIKPLQ 540
  541 LQIVIACGTM ARQLDAARLL APLIDTFVQL LQSCQIDDEF VVQLLYVFLQ FLKHKELSAR 600
  601 LMTQDSALGA HMIDLMHDAN AVVREVCDNA LLIMGEHSKE WAKRIAGERF KWHNAQWLEM 660
  661 VERDDSEFVD YDDEDFGADL KFDHYDDGFD MNEPLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] PSI-BLAST 54.39794 Structure of the Kap60p:Nup2 complex
    2 View Details [101..696] PSI-BLAST 62.0 Crystal structure of beta-catenin/ICAT helical domain/unphosphorylated APC R3

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • protein transporter activity
    		•  3.05338750264476 bayes_pls_golite062009
  • protein binding
    		•  2.78733902345842 bayes_pls_golite062009
  • binding
    		•  2.6374633159018 bayes_pls_golite062009
  • transporter activity
    		•  1.55621630624352 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.33334123659384 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.23804310697631 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  1.15447282085461 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.698613639309592 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.425403776087115 bayes_pls_golite062009
  • actin binding
    		•  0.360199499297314 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.350388174853674 bayes_pls_golite062009
  • signal sequence binding
    		•  0.27824906981293 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  0.237512539263598 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.141331164449492 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.0332743336452223 bayes_pls_golite062009
  • RNA binding
    		•  0.0287526191298597 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.0268373969988844 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.00234756529236324 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle