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Protein Overview: CE30649

General Information:
Name(s) found: CE30649 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00017268 locus:hmgr-1 status:Confirmed UniProt:Q19207 protein_id:CCD69058.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 550 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    lipid metabolic process [IEALink to PubMed article]
    biosynthetic process [IEALink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: hydroxymethylglutaryl-CoA reductase activity [IEALink to PubMed article]
    hydroxymethylglutaryl-CoA reductase (NADPH) activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVADKRKLLD FLQSCDISDE ASRKIENFIC ENYDQKEKPK RKPLFSVGED DDSEEYVSPI  60
   61 KETCETGTQC KRDVEYPEIE SGNRSLDEIS REWKECKDVT PGEAVRLLRR GQAKSRELES 120
  121 RFPAEQAIPI RRTFINKKFE NLPYLGYDYT LATECCCENV IGYTPVPVGV AGPLTLNGTS 180
  181 EIYVPMATTE GALIASTNRG MNVIRAAGGV ETSIFNSGMT RAPVVKFPTA RDAVSMKRWL 240
  241 EHPENQDRAR QEFQSCSRFA KLKSIDITID GNLAYLRFDA HTGDAMGMNM ISKSCDSTMR 300
  301 FLMENFPEMT VLALSGNLCV DKKAAAKNWT EGRGRSVVAE CLIPREVVTK TLRTTPEQLA 360
  361 YLTTTKLHIG SSRAGAVGGS NAHAANIVAA IFIATGQDAA QVVSSSMCST RMEVTADKNL 420
  421 YVSCTLPCVE VGTVGGGTIL APQRACLESL GCAGPNKEQP GQNAERLAEV IAATVLAGEL 480
  481 SLMAALTTNE LVSSHMKLNR SKQQLYADDS GKATHFEKEV EKAGSLLSGK SGNIKLKRLP 540
  541 QDVVQCSNIL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..550] PSI-BLAST 175.0 NAD-binding domain of HMG-CoA reductase; Substrate-binding domain of HMG-CoA reductase


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle