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Protein Overview: CE29745

General Information:
Name(s) found: CE29745 [WormBase]
Description(s) found:
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  • WBGene00017062 locus:glrx-3 status:Confirmed UniProt:H2KZJ5 protein_id:CCD68478.1 [WormBase]
  • gi|71988153|ref|NP_001023756.1| hypothetical protein D2063.3 [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_741524.1| thioredoxin-like 2 (38.5 kD) (5E818) [Caenorhabditis elegans] [NCBI NR]
  • gi|16604139|gb|AAL27238.1|AF125951_3 Hypothetical protein D2063.3a [Caenorhabditis elegans] [NCBI NR]
  • [wormpep79.fasta]
  • CE29745 WBGene00017062 status:Confirmed TR:Q95X14 protein_id:AAL27238.1 [wormpep150.fasta]
  • 29745 WBGene00017062 status:Confirmed TR:Q95X14 protein_id:AAL27238.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • thioredoxin-like 2 (38.5 kD) (5E818) [Caenorhabditis elegans]gi|16604139|gb|AAL27238.1| Hypothetical protein D2063.3a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • status:Confirmed TR:Q95X14 protein_id:AAL27238.1 [wormpep115.fasta.reversed]
  • CE29745 status:Confirmed TR:Q95X14 protein_id:AAL27238.1 [wormpep80.hongbin]
  • CE29745 WBGene00017062 status:Confirmed UniProt:Q95X14_CAEEL protein_id:AAL27238.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE29745 WBGene00017062 status:Confirmed UniProt:Q95X14_CAEEL protein_id:AAL27238.1| [wormORF-contam.fasta]
  • Hypothetical protein D2063.3a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • D2063.3a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE29745 WBGene00017062 status:Confirmed UniProt:Q95X14 protein_id:AAL27238.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE29745 WBGene00017062 locus:glrx-3 status:Confirmed UniProt:H2KZJ5 protein_id:CCD68478.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • GLutaRedoXin OS=Caenorhabditis elegans GN=glrx-3 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 345 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: electron transport [IEALink to PubMed article]
    glycerol ether metabolic process [IEALink to PubMed article]
    cell redox homeostasis [IEALink to PubMed article]
    Molecular Function: protein disulfide oxidoreductase activity [IEALink to PubMed article]
    electron carrier activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIQEIKSGE EVAAFIKEPS PAVLHFYASW APSCEQVNQL LDDLLAEIAL PLRAAFIDAE  60
   61 ALPGISLNFK ITAAPTLVFF SNGKEVDRID GFVPKEIQSK VVLVASRSLS QSSSDASSTT 120
  121 SSTPSLTPQQ EKEALNARLG ALVNSQKVMV FMKGDPSAPR CGFSRTIVEL LNSHKIKFGS 180
  181 FDIFSDEAVR QGLKEYSNWP TYPQLYFDGE LIGGLDVVKE EFSDPQFIKQ LPKVGENSEG 240
  241 GSLEDRLKKL VSSQRLMLFM KGDRETPKCG FSRTIVDLLN KARADYHTFD ILEDEEVRQG 300
  301 LKKFSNWPTY PQLYLDGELV GGLDVVKEEL LDTHFLRQIP RIRND

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..228] PSI-BLAST 14.522879 C-terminal, Grx domain of Hybrid-Prx5; N-terminal, Prx domain of Hybrid-Prx5
    2 View Details [229..345] PSI-BLAST 29.154902 Solution structure of Grx4, a monothiol glutaredoxin from E. coli.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • antioxidant activity
    		•  3.66884588063322 bayes_pls_golite062009
  • peroxidase activity
    		•  3.43831566988273 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  3.43831566988273 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  2.56524997297011 bayes_pls_golite062009
  • peroxiredoxin activity
    		•  2.12777217096121 bayes_pls_golite062009
  • thioredoxin peroxidase activity
    		•  1.96134566495756 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.90357236955554 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  1.8187537496904 bayes_pls_golite062009
  • protein disulfide oxidoreductase activity
    		•  1.47769936616412 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  1.32811008894503 bayes_pls_golite062009
  • binding
    		•  1.25802922431343 bayes_pls_golite062009
  • selenium binding
    		•  1.1082524159827 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • transferase activity
    		•  0.245320538630117 bayes_pls_golite062009
  • protein binding
    		•  0.134341907247724 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle