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View Structure Prediction Details

Protein: CE29745
Organism: Caenorhabditis elegans
Length: 345 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE29745.

Description E-value Query
Range
Subject
Range
gi|50749993 - gi|50749993|ref|XP_421826.1| PREDICTED: similar to thioredoxin-like [Gallus gallus]
256.0 [0..3] [340..6]

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Predicted Domain #1
Region A:
Residues: [1-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIQEIKSGE EVAAFIKEPS PAVLHFYASW APSCEQVNQL LDDLLAEIAL PLRAAFIDAE  60
   61 ALPGISLNFK ITAAPTLVFF SNGKEVDRID GFVPKEIQSK VVLVASRSLS QSSSDASSTT 120
  121 SSTPSLTPQQ EKEALNARLG ALVNSQKVMV FMKGDPSAPR CGFSRTIVEL LNSHKIKFGS 180
  181 FDIFSDEAVR QGLKEYSNWP TYPQLYFDGE LIGGLDVVKE EFSDPQFI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1nm3A
Description: C-terminal, Grx domain of Hybrid-Prx5; N-terminal, Prx domain of Hybrid-Prx5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antioxidant activity 3.66884588063322 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
transcription regulator activity 1.90357236955554 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.8187537496904 bayes_pls_golite062009
protein disulfide oxidoreductase activity 1.47769936616412 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
selenium binding 1.1082524159827 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
transferase activity 0.245320538630117 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [229-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQLPKVGENS EGGSLEDRLK KLVSSQRLML FMKGDRETPK CGFSRTIVDL LNKARADYHT  60
   61 FDILEDEEVR QGLKKFSNWP TYPQLYLDGE LVGGLDVVKE ELLDTHFLRQ IPRIRND

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.154902
Match: 1ykaA
Description: Solution structure of Grx4, a monothiol glutaredoxin from E. coli.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle