Protein Overview: egl-8

General Information:
Name(s) found:	egl-8 / CE30588 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00001177 locus:egl-8 status:Confirmed UniProt:Q95X30 protein_id:CCD61782.1 [WormBase] gi\|71981791\|ref\|NP_001021346.1\| EGg Laying defective family member (egl-8) [Caenorhabditis elegans] [NCBI NR] ref\|NP_503126.2\| EGg Laying defective EGL-8, Posterior BOdy contraction defect in defecation PBO-2, phospholipase C beta homolog (159.5 kD) (egl-8) [Caenorhabditis elegans] [NCBI NR] gi\|18652576\|gb\|AAL77167.1\|AF068714_3 Egg laying defective protein 8, isoform a [Caenorhabditis elegans] [NCBI NR] [wormpep79.fasta] CE30588 WBGene00001177 locus:egl-8 phospholipase status:Confirmed TR:Q95X30 protein_id:AAL77167.1 [wormpep150.fasta] 30588 WBGene00001177 locus:egl-8 phospholipase status:Confirmed TR:Q95X30 protein_id:AAL77167.1 [wormpep130-phg-ecoli-orf-rand.fasta] EGg Laying defective EGL-8, Posterior BOdy contraction defect in defecation PBO-2, phospholipase C beta homolog (159.5 kD) (egl-8) [Caenorhabditis elegans]gi\|18652576\|gb\|AAL77167.1\| Egg laying defective protein 8, isoform a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] locus:egl-8 phospholipase status:Confirmed TR:Q95X30 protein_id:AAL77167.1 [wormpep115.fasta.reversed] CE30588 locus:egl-8 phospholipase status:Confirmed [wormpep80.hongbin] CE30588 WBGene00001177 locus:egl-8 phospholipase status:Confirmed UniProt:Q95X30_CAEEL protein_id:AAL77167.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE30588 WBGene00001177 locus:egl-8 phospholipase status:Confirmed UniProt:Q95X30_CAEEL protein_id:AAL77167.1\| [wormORF-contam.fasta] EGg Laying defective family member (egl-8) [Caenorhabditis elegans] [nr-271106-contam.fasta] Egg laying defective protein 8, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta] CE30588 WBGene00001177 locus:egl-8 phospholipase status:Confirmed UniProt:Q95X30 protein_id:AAL77167.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE30588 WBGene00001177 locus:egl-8 phospholipase status:Confirmed UniProt:Q95X30 protein_id:CCD61782.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE30588 WBGene00001177 locus:egl-8 status:Confirmed UniProt:G5EBH0 protein_id:CCD61782.1 [wormpep246-ecoli-contam.fasta] CE30588 WBGene00001177 locus:egl-8 status:Confirmed UniProt:G5EBH0 protein_id:CCD61782.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta] Isoform of G5EBH0, Isoform a of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 OS=Caenorhabditis elegans GN=egl-8 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	1419 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	regulation of pharyngeal pumping [IGI][IMP] regulation of oviposition [IMP] regulation of locomotion [IGI] signal transduction [IEA] positive regulation of growth rate [IMP ] embryonic development ending in birth or egg hatching [IMP] lipid metabolic process [IEA] dopamine receptor signaling pathway [IMP] positive regulation of locomotion [IMP]
Molecular Function:	phosphoinositide phospholipase C activity [IEA] phospholipase C activity [IEA] calcium ion binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKEFQFNWK PTIIPELLHG SVFDRYDDES TCLELNAQVR IDENGFFLRW LIEGKDAVVL  60
   61 DMGQIWEART GGLPKDGRIM FELEQRGASE TIAERTIWIT HGQDLVNVQS FFLVAESVEL 120
  121 AKTCRAGIND ILKSSRIRHV CPTTQLMKYH TWLTMNVNER RKIPIKLIIK TFSSGKPEKM 180
  181 VQKCLNDLGL GGDKYTPARV INRSMGKKFR NFYKCSRGRK RKEREELDVD ILTFEKFQRL 240
  241 YNKICPRTEV QELFVKLSGQ KEYLTKERLI NFLNEEQRDP RLNEILFPFF DSQRIVALLK 300
  301 KHENDIKYQE DGKMSGDGFL RFLMSDENPP VFLDRIEMFM DMDQPLCHYY INSSHNTYLT 360
  361 GRQYGGKSSS EIYRQVLLSG CRCIELDCWD GTGENKGEPI ITHGKAMCTD VFFKDVLVQI 420
  421 RDTAFARSDF PVVLSFENHC SKSNQLKMAK YCMDIFGDML LSKPFEDAPL DPGVSLPSPN 480
  481 RLRKKILIKN KRLKTDIERH QLDQFLREGK LDEEDELNET PEVVGEDSVS PRSGGSGGTG 540
  541 APEEVDDDTS DDDDDPSVQT SLNVMRTIPT VNTTSNNGSN RSARSSLDTP SPSGGSLMVP 600
  601 DRATSTATSI KNAVLARSPN FSSLRQKLSF KRRQSPLAGD QRAHPEVEQP VSSSSPATPS 660
  661 ISGPPPCATS SGSTSSITIT TTGCSTSSSG PSKHILGGEM PAKENDEAHP ELKQNFIAKN 720
  721 LKGFGFSKKQ PVLTKEEEER IFAEYHYTGA TTNIHPLLSS LVNYTHPVKF SGFDVAEANN 780
  781 LHFHMSSFSE STGLGYLKQS APEFVNYNKR QSSRIYPKGA RVDSSNFLPQ IFWNAGCQMV 840
  841 SLNFQTPDVY MQLNMGKFEY NGGSGYLLKP DFLRRPDRTF DPFSESPVDG VIAAHCSVRV 900
  901 ISGQFLSDRK IGTYVEVEMY GLPTDTIRKE HKTKVIPGNG LNPVYNEDPF VFRKVVLPEL 960
  961 AVLRFAVYDE NGKQLGQRIL PLDGLQAGYR HISLRSDTNQ SFILSPVLFV QIVIKTYVPD1020
 1021 ELSGLVDALA DPRAFLSEQK KRQEALAHMG VDDSDIPDVP NTRNMALRHV KQPPRQNGSS1080
 1081 ADLLANNGQT GSARGDQTSS MASSTIRSPN EQPQPVAVDK FKVDPIEVDD LRRDKAFAKL1140
 1141 LKRFQKELDD LRKKHQKQRD SIQKQQQTNV DKLITNNRRS TKKEKGSRRS LTASVSSGCG1200
 1201 SASGTVTVSV CSPSGASCSG YSTGGPSTPV ACNSDGTGSP ATIGSPVPQD LVNNDRVRSL1260
 1261 VNTQTGEWSA MVRRHDEEEF ELKKVQLKEQ FDLLRKLMSE AQKNQMLALK LRLEAEGKDL1320
 1321 KQTQTKKSME DAKVIQLDKG IKTKAERDRR VKELNEKNLK MFVEERKRLA MKAQKHEEQL1380
 1381 TKRHLDQLEQ LDKDFHKALD AEVGNYKEEQ LAAQPTSVV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: egl-8

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: