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Protein Overview: asm-1

General Information:
Name(s) found: asm-1 / CE30230 [WormBase]
Description(s) found:
Found 20 descriptions.
SHOW ALL
  • WBGene00000211 locus:asm-1 Sphingomyelin phosphodiesterase 1 status:Confirmed UniProt:Q10916 protein_id:CCD61537.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 564 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IDALink to PubMed article]
    Biological Process: sphingomyelin catabolic process [IDALink to PubMed article][IEALink to PubMed article]
    Molecular Function: sphingomyelin phosphodiesterase activity [IDALink to PubMed article][IEALink to PubMed article]
    hydrolase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIIYLISTV LLIYTNATVL RTKESIQNKV TYDKYGFQPL CISCTGLISV ASFFLKFDVS  60
   61 EPVILEFATI VCKLFAKQPW AVCDGISSQF RDEFFYVFRR LANESPSQIC GIILPDCADP 120
  121 TDPSESGWMV ALPPKPKRTR ISKKKVQKKP NMSMSQNLNV LQLTDLHVDF EYKYPSEANC 180
  181 DDPVCCRVSV SEPKKAAGYW GSVGKCDIPF WTVENMLSHI NKTHMIDMVI MTGDYINHVD 240
  241 WEYSIEEHLS VLRKLHRLVQ NTFPSTPIYW ALGNHEGVPV NSFAPHSVDE RFWPTWLYKE 300
  301 FQTMSGPWLS EGAKDSLLKR GSYSTQVMDG LKLITLNTGF CEVTNFFLYL NQSDPDSSMS 360
  361 WFVKELFESE KKGEQVYVLA HIPPGDSECL EGWAFNYYRV IQRFSSTIAA QFFGHDHLDY 420
  421 FTVFYEDMHN VSSKPISVGY ASPSVTTFEY QNPAYRIYEI DPYNKFKIVD FTTYYADLEK 480
  481 ATEDKKPVWE KLYSARQAHG MDDLSPLSWN KVIQKLFTSE KKREKFYQYA FRNFSPQCDS 540
  541 TCQMQLMCNL RMGHHNSTLY CPTF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..102] PSI-BLAST 14.522879 Saposin C
    2 View Details [103..564] PSI-BLAST 37.69897 Purple acid phosphatase, N-terminal domain; Plant purple acid phosphatase, catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.50771902135158 bayes_pls_golite062009
    2
    Term Confidence Notes
  • phosphoric ester hydrolase activity
    		•  3.1640402146807 bayes_pls_golite062009
  • hydrolase activity
    		•  2.06280293513737 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.62419884857008 bayes_pls_golite062009
  • signal transducer activity
    		•  1.5323377955218 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.5323377955218 bayes_pls_golite062009
  • catalytic activity
    		•  1.39852585255405 bayes_pls_golite062009
  • protein binding
    		•  1.33435965029646 bayes_pls_golite062009
  • binding
    		•  1.01605260539008 bayes_pls_golite062009
  • phosphatase activity
    		•  0.887417749186372 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  0.744264552706022 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  0.707342350941796 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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