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Protein Overview: mrt-2

General Information:
Name(s) found: mrt-2 / CE29376 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00003417 locus:mrt-2 status:Confirmed UniProt:G5EC44 protein_id:CAB63359.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 267 amino acids

    Gene Ontology:
    Cellular Component: PCNA complex [IEALink to PubMed article]
    nucleus [ICLink to PubMed article][IEALink to PubMed article]
    Biological Process: DNA damage checkpoint [IMPLink to PubMed article]
    DNA repair [IEALink to PubMed article][IMPLink to PubMed article]
    telomere maintenance [IMPLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    DNA damage response, signal transduction resulting in induction of apoptosis [IMPLink to PubMed article]
    regulation of DNA replication [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    DNA polymerase processivity factor activity [IEALink to PubMed article]
    exonuclease activity [IEALink to PubMed article]
    damaged DNA binding [IEALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMELETGQCT IMELKKENVK ELAQVFKTVA FKDTGTWHAS EAGMKITVDD GSYQLASVFI  60
   61 NPAFFSSFKV REEIVSMKIS IKSISEFLSI SENSSSSVKV SYPGMFQPVK MLVEDADGWV 120
  121 ARGNFTTTLA DQELDFEFDD AGVLATYLLK TQVLKEIIKD FDDTSRTVRI QFTKNSLCFT 180
  181 TFGDVGETTV SIPSRSLQME SVKCLEEVEF SYLLSLIQRM TTAFILATKL ILRVDERGVL 240
  241 SCQFSIDHGE GNASYIEFLT VPADEEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..267] PSI-BLAST 70.39794 Prolifirating cell nuclear antigen (PCNA)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA polymerase activity
    		•  4.03805427520849 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  4.03676997767928 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  2.73498799665327 bayes_pls_golite062009
  • binding
    		•  1.88302251910664 bayes_pls_golite062009
  • protein binding
    		•  1.50334902588177 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.30503066394007 bayes_pls_golite062009
  • DNA binding
    		•  1.08991130379715 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.82032718298306 bayes_pls_golite062009
  • catalytic activity
    		•  0.48077242755678 bayes_pls_golite062009
  • DNA polymerase processivity factor activity
    		•  0.35827096673638 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.252286203059537 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle