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Protein Overview: apn-1

General Information:
Name(s) found: apn-1 / CE28953 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00000151 locus:apn-1 DNA-(apurinic or apyrimidinic site) lyase status:Confirmed UniProt:Q10002 protein_id:CAA87789.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 396 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: DNA repair [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    endonuclease activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANKKVTFRE DVKSPAIRKL KQKLTPLKIK KGRGKIQKHI QKTLQKMKEE EESENQSPGT  60
   61 TVEETLTEEN ISTDKEETSK LENKPKKTRK TSGETIAQKK SRETVGVEVL KTSEGSSKML 120
  121 GFHVSAAGGL EQAIYNARAE GCRSFAMFVR NQRTWNHKPM SEEVVENWWK AVRETNFPLD 180
  181 QIVPHGSYLM NAGSPEAEKL EKSRLAMLDE CQRAEKLGIT MYNFHPGSTV GKCEKEECMT 240
  241 TIAETIDFVV EKTENIILVL ETMAGQGNSI GGTFEELKFI IDKVKVKSRV GVCIDTCHIF 300
  301 AGGYDIRTQK AYEEVMKNFG EVVGWNYLKA IHINDSKGDV GSKLDRHEHI GQGKIGKAAF 360
  361 ELLMNDNRLD GIPMILETPE GKYPEEMMIM YNMDKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] FFAS03 0.981 Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography
    2 View Details [113..396] PSI-BLAST 71.0 Endonuclease IV

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  1.66019571685402 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  0.97458966528485 bayes_pls_golite062009
  • DNA-(apurinic or apyrimidinic site) lyase activity
    		•  0.36517654808269 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  0.19550406288989 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle