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View Structure Prediction Details

Protein: apn-1
Organism: Caenorhabditis elegans
Length: 396 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for apn-1.

Description E-value Query
Range
Subject
Range
gi|112434021 - gi|112434021|gb|ABI18361.1| endonuclease IV [Enterobacter pyrinus]
270.0 [0..117] [391..1]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANKKVTFRE DVKSPAIRKL KQKLTPLKIK KGRGKIQKHI QKTLQKMKEE EESENQSPGT  60
   61 TVEETLTEEN ISTDKEETSK LENKPKKTRK TSGETIAQKK SRETVGVEVL KT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.981
Match: 2d57A
Description: Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [113-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEGSSKMLGF HVSAAGGLEQ AIYNARAEGC RSFAMFVRNQ RTWNHKPMSE EVVENWWKAV  60
   61 RETNFPLDQI VPHGSYLMNA GSPEAEKLEK SRLAMLDECQ RAEKLGITMY NFHPGSTVGK 120
  121 CEKEECMTTI AETIDFVVEK TENIILVLET MAGQGNSIGG TFEELKFIID KVKVKSRVGV 180
  181 CIDTCHIFAG GYDIRTQKAY EEVMKNFGEV VGWNYLKAIH INDSKGDVGS KLDRHEHIGQ 240
  241 GKIGKAAFEL LMNDNRLDGI PMILETPEGK YPEEMMIMYN MDKR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.0
Match: 1qtwA
Description: Endonuclease IV
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.66019571685402 bayes_pls_golite062009
deoxyribonuclease activity 0.97458966528485 bayes_pls_golite062009
DNA-(apurinic or apyrimidinic site) lyase activity 0.36517654808269 bayes_pls_golite062009
endodeoxyribonuclease activity 0.19550406288989 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle