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Protein Overview: rnp-2

General Information:
Name(s) found: rnp-2 / CE28597 [WormBase]
Description(s) found:
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  • WBGene00004385 locus:rnp-2 status:Confirmed UniProt:Q21322 protein_id:CCD72715.1 [WormBase]
  • gi|17541324|ref|NP_500504.1| RNP (RRM RNA binding domain) containing family member (rnp-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|15055398|gb|AAA98032.2| Rnp (rrm rna binding domain) containing protein 2 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE28597 WBGene00004385 locus:rnp-2 U1 small nuclear ribonucleoprotein A status:Confirmed TR:Q21322 protein_id:AAA98032.2 [wormpep150.fasta]
  • 28597 WBGene00004385 locus:rnp-2 U1 small nuclear ribonucleoprotein A status:Confirmed TR:Q21322 protein_id:AAA98032.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • small nuclear ribonucleoprotein (rnp-2) [Caenorhabditis elegans]gi|15055398|gb|AAA98032.2| Rnp (rrm rna binding domain) containing protein 2 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:rnp-2 U1 small nuclear ribonucleoprotein A status:Confirmed TR:Q21322 protein_id:AAA98032.2 [wormpep115.fasta.reversed]
  • CE28597 U1 small nuclear ribonucleoprotein A status:Confirmed TR:Q21322 protein_id:AAA98032.2 [wormpep80.hongbin]
  • CE28597 WBGene00004385 locus:rnp-2 U1 small nuclear ribonucleoprotein A status:Confirmed UniProt:Q21322_CAEEL protein_id:AAA98032.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE28597 WBGene00004385 locus:rnp-2 U1 small nuclear ribonucleoprotein A status:Confirmed UniProt:Q21322_CAEEL protein_id:AAA98032.2| [wormORF-contam.fasta]
  • RNP (RRM RNA binding domain) containing family member (rnp-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Rnp (rrm rna binding domain) containing protein 2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE28597 WBGene00004385 locus:rnp-2 U1 small nuclear ribonucleoprotein A status:Confirmed UniProt:Q21322 protein_id:AAA98032.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE28597 WBGene00004385 locus:rnp-2 U1 small nuclear ribonucleoprotein A status:Confirmed UniProt:Q21322 protein_id:CCD72715.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE28597 WBGene00004385 locus:rnp-2 status:Confirmed UniProt:Q21322 protein_id:CCD72715.1 [wormpep246-ecoli-contam.fasta]
  • RNP (RRM RNA binding domain) containing OS=Caenorhabditis elegans GN=rnp-2 PE=1 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 206 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: RNA interference [IMP]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEVAPNSTL YINNLNEKIK IDELRKSLVA VFKQFGEIVS VMCFRTLKMR GQAHVIFKEL  60
   61 PAASAAREAL NGFPFYEKPM RIQFAREDSD VVAQEKGTYI KREPKYLSEK ILKKPKSRKK 120
  121 ENGGDGPAPP NKILFCTNLP DSATAEMLEI MFNQFAGLKD IRMVPNRPGI AFVEFDTDSL 180
  181 AIPARTTLNN FKISAEHTMR VDYAKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] PSI-BLAST 19.69897 RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES
    2 View Details [102..206] PSI-BLAST 17.221849 RNA BINDING DOMAIN 2 OF HUMAN U1A PROTEIN, NMR, 20 STRUCTURES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • U1 snRNA binding
    		•  4.22094068431436 bayes_pls_golite062009
  • snRNA binding
    		•  4.06596327298973 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.92450390013691 bayes_pls_golite062009
  • DNA binding
    		•  1.8021593476478 bayes_pls_golite062009
  • structural molecule activity
    		•  1.29928829870122 bayes_pls_golite062009
  • transcription factor activity
    		•  1.15127506309683 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.591700155096213 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
    2
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • U1 snRNA binding
    		•  4.22094068431436 bayes_pls_golite062009
  • snRNA binding
    		•  4.06596327298973 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.92450390013691 bayes_pls_golite062009
  • DNA binding
    		•  1.8021593476478 bayes_pls_golite062009
  • structural molecule activity
    		•  1.29928829870122 bayes_pls_golite062009
  • transcription factor activity
    		•  1.15127506309683 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.591700155096213 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle