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Protein Overview: ser-1

General Information:
Name(s) found: ser-1 / CE28481 [WormBase]
Description(s) found:
Found 23 descriptions.
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  • WBGene00004776 locus:ser-1 status:Confirmed UniProt:O17470 protein_id:CCD63419.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 683 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: G-protein coupled receptor protein signaling pathway [IEALink to PubMed article]
    serotonin receptor signaling pathway [IDALink to PubMed article]
    calcium-mediated signaling [IDALink to PubMed article]
    Molecular Function: serotonin binding [IDALink to PubMed article]
    amine binding [IDALink to PubMed article]
    serotonin receptor activity [IDALink to PubMed article]
    rhodopsin-like receptor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIELFSHSA PPEDPYYVPA NESFATTALT PHFSTTSVWS IRVQLIPTMG IYHFNGVALF  60
   61 LLPVLCLIGL IGNFLVCVAI ATDRRLHNVT NYFLFSLALA DLLVCCIVMP LSIVVEVRHG 120
  121 VWTWSVSMCL LYVYSDVFLC SASIVHMSVI SLDRYLGISQ PLRTRNRSKT LIFIKIAIVW 180
  181 VVTLLVSCPI AVLAMHDTAN ILRNNQCMIF SRYYIIYGST MTFLIPLCIM GVTYAKTTQL 240
  241 LNKQASILSQ KAGDKFNGNG LRRTMPHRKL GYARTYSATV NGTIANGKAI GAHGRTMSSI 300
  301 SNIANGETAD RLGTSRPSIN TNGHKQLQKA STINKWKSRT SNLVTNFANK VGRRSSLQTA 360
  361 TQDLANEHKA TRVLAVVFAC FFICWTPFFF INFLIGFGGE NVQIPDWVAS IFLWLGYVSS 420
  421 TINPIIYTVF NKRFRQAFVR ILRCQCFHPL RDSHQMYSRN FTTTIVPDTY TCSRSNQERT 480
  481 TSVITRDETR SARSSERPEP SRARSEISEE PVARTNGKLT SEKKKISLPS FPRVSSSRDS 540
  541 RATTEASTTD EETKPLIPKS TVPATVINIP EQLINPIKKS LTTIINMPLL DETIPEKAQV 600
  601 HHKSQTLLTS STLNFATFST CPQQPTRSYS CVDCKKAEKM LSSDVSDMMT TSTASTASTV 660
  661 NGAPRKHLTL FNHFDSAIKE TFL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..338] PSI-BLAST 52.0 Rhodopsin
    2 View Details [339..488] FFAS03 3.74 Rhodopsin
    3 View Details [489..683] MSA 5.051996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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