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Protein Overview: ced-2

General Information:
Name(s) found: ced-2 / CE28360 [WormBase]
Description(s) found:
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  • WBGene00000416 locus:ced-2 Cell death abnormality protein 2 status:Confirmed UniProt:Q9NHC3 protein_id:CCD66714.1 [WormBase]
  • gi|75024165|sp|Q9NHC3.1|CED2_CAEEL RecName: Full=Cell death abnormality protein 2; AltName: Full=Cell-corpse engulfment protein CED-2 [NCBI NR]
  • gi|6969624|gb|AAF33845.1|AF226866_1 cell-corpse engulfment protein CED-2 [Caenorhabditis elegans] [NCBI NR]
  • gi|17539468|ref|NP_500105.1| CEll Death abnormality family member (ced-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|14574323|gb|AAK68463.1|AC024776_5 Cell death abnormality protein 2, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • Cell death abnormality protein 2 OS=Caenorhabditis elegans GN=ced-2 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE28360 WBGene00000416 locus:ced-2 status:Confirmed TR:Q9NHC3 protein_id:AAK68463.1 [wormpep150.fasta]
  • 28360 WBGene00000416 locus:ced-2 status:Confirmed TR:Q9NHC3 protein_id:AAK68463.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CEll Death abnormality CED-2, cell-corpse engulfment and cell migration protein, an adaptor protein similar to metazoan adaptor protein Crk and viral v-crk oncogene (30.9 kD) (ced-2) [Caenorhabditis elegans]gi|14574323|gb|AAK68463.1| Cell death abnormali [nrdb_11152004_Chlamydomonas]
  • locus:ced-2 status:Confirmed TR:Q9NHC3 protein_id:AAK68463.1 [wormpep115.fasta.reversed]
  • CE28360 locus:ced-2 status:Confirmed [wormpep80.hongbin]
  • CE28360 WBGene00000416 locus:ced-2 status:Confirmed UniProt:Q9NHC3_CAEEL protein_id:AAK68463.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE28360 WBGene00000416 locus:ced-2 status:Confirmed UniProt:Q9NHC3_CAEEL protein_id:AAK68463.1| [wormORF-contam.fasta]
  • CEll Death abnormality family member (ced-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Cell death abnormality protein 2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • cell-corpse engulfment protein CED-2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE28360 WBGene00000416 locus:ced-2 status:Confirmed UniProt:Q9NHC3 protein_id:AAK68463.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE28360 WBGene00000416 locus:ced-2 status:Confirmed UniProt:Q9NHC3 protein_id:CCD66714.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE28360 WBGene00000416 locus:ced-2 status:Confirmed UniProt:Q9NHC3 protein_id:CCD66714.1 Cell death abnormality protein 2 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 279 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [NASLink to PubMed article]
    Biological Process: engulfment of apoptotic cell [IMPLink to PubMed article]
    cell migration [IMPLink to PubMed article]
    programmed cell death [IMPLink to PubMed article]
    Molecular Function: SH3/SH2 adaptor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTNGFDPFE WRSFYFPGMS REEAHKLLGE PQVSIGTFLM RDSSRPGEYS LTVREADEGN  60
   61 AVCHYLIERG EPKEDGTAAA GVKIANQSFP DIPALLNHFK MRVLTEASLL AAYKKPIIEV 120
  121 VVGTFKFTGE RETDLPFEQG ERLEILSKTN QDWWEARNAL GTTGLVPANY VQIQMEFHND 180
  181 RTSKGASQSS IGSSGGGAER FSSASTSSDN IELQPRLPAK AKVTFDRVPN AYDPTQLRVK 240
  241 KGQTVLVTQK MSNGMYKAEL DGQIGSVPHT YLRFTAVSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..279] PSI-BLAST 26.69897 No description for 2eyzA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle