Protein Overview: uba-4

General Information:
Name(s) found:	uba-4 / CE28320 [WormBase]
Description(s) found: Found 21 descriptions. SHOW ALL	WBGene00018357 locus:moc-3 Adenylyltransferase and sulfurtransferase MOCS3 status:Confirmed UniProt:O44510 protein_id:CCD61405.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	402 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA]
Biological Process:	hermaphrodite genitalia development [IMP] Mo-molybdopterin cofactor biosynthetic process [IEA]
Molecular Function:	catalytic activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDDQWVAGI SKKDAGRYSR QLLVDDFGVS GQKNLKNLNV LIVGAGGLGC PVATYLGAAG  60
   61 IGTIGIVDYD HISLDNLHRQ VAYKEDQVGK SKAQALADNI KLQNSDLNVQ VHNTSLDSSN 120
  121 AMQLFKNYEI VCDCTDNVAT RYLINDVCVL LNIPLVSGSA LRWDGQLSVY HYGSDCPCYR 180
  181 CLFPSPPDPN SVTNCNEGGV LGPIVGVIGS MQALEVMKIA AKVRTTLAGQ LLLFDGREGK 240
  241 SRTIRLRKRD PKCEVCGDNP TITAPIDYVL FCGAGAHDKI ENLKLLELSD RVNVTEYRNK 300
  301 RREQKPVLLD TRPSLEFEIA HLPEAINVTL KECRSLSAED ISNRLGLQNT EHSDVFVICH 360
  361 RGNDSQRAVL LLREKLVDIK FRDIIGGYEQ WALKINDMFP LY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..260]	PSI-BLAST	68.0	Molybdenum cofactor biosynthesis protein MoeB
2	View Details	[261..402]	PSI-BLAST	8.045757	Sulfurtransferase GlpE

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
URM1 activating enzyme activity	5.44388923879076	bayes_pls_golite062009
small protein activating enzyme activity	3.58068602287881	bayes_pls_golite062009
NEDD8 activating enzyme activity	2.11391077579348	bayes_pls_golite062009
thiosulfate sulfurtransferase activity	2.05168889065215	bayes_pls_golite062009
small conjugating protein ligase activity	1.84216910649062	bayes_pls_golite062009
binding	1.46180162036652	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.31244773198273	bayes_pls_golite062009
acid-amino acid ligase activity	1.27535252106053	bayes_pls_golite062009
transcription regulator activity	1.23669539775752	bayes_pls_golite062009
catalytic activity	1.22201444897049	bayes_pls_golite062009
ligase activity	0.886082936938522	bayes_pls_golite062009
transferase activity	0.680338489823338	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.302798969355962	bayes_pls_golite062009
protein binding	0.258795594127926	bayes_pls_golite062009

2

Term	Confidence	Notes
thiosulfate sulfurtransferase activity	4.07143118207301	bayes_pls_golite062009
binding	1.53109235820839	bayes_pls_golite062009
transferase activity	1.00600613068372	bayes_pls_golite062009
phosphoprotein phosphatase activity	0.765055251775806	bayes_pls_golite062009
catalytic activity	0.687308230067573	bayes_pls_golite062009
phosphatase activity	0.596156043915887	bayes_pls_golite062009
sulfurtransferase activity	0.419061082217665	bayes_pls_golite062009
protein binding	0.415782692658192	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.41208200336081	bayes_pls_golite062009
protein tyrosine phosphatase activity	0.224132693583958	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.58

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle