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Protein Overview: hmg-1.2

General Information:
Name(s) found: hmg-1.2 / CE28233 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00001972 locus:hmg-1.2 High mobility group protein 1.2 status:Confirmed UniProt:Q09390 protein_id:CCD83370.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 234 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: vulval development [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    gamete generation [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    gonad development [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    Wnt receptor signaling pathway [IGILink to PubMed article]
    cell fate specification [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSGYSANIF PSSSSPTLYQ SHQLPNPSAT MYQATPRDMG KPPVRGKTSP YGFFVKMCYE  60
   61 EHKKKYPNEN VQVTEISKKC SEKWKTMVDD EKRRFYELAQ KDAERYQAEV SVAAYGGEDA 120
  121 MRKRKRAKKD PHAPKRALSA FFFYSQDKRP EIQAGHPDWK VGQVAQELGK MWKLVPQETK 180
  181 DMYEQKAQAD KDRYADEMRN YKAEMQKMSG MDHYDDDNIH HVVHVEDINS QNIS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..234] PSI-BLAST 28.0 No description for 2gzkA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.28152434895694 bayes_pls_golite062009
  • DNA binding
    		•  1.84781463420276 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.65696822227413 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.61604561096523 bayes_pls_golite062009
  • beta-catenin binding
    		•  1.41213253616358 bayes_pls_golite062009
  • transcription factor activity
    		•  0.79924481726919 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.61748685686195 bayes_pls_golite062009
  • protein binding
    		•  0.413179898438205 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle