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Protein Overview: acr-7

General Information:
Name(s) found: acr-7 / CE28078 [WormBase]
Description(s) found:
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  • WBGene00000046 locus:acr-7 Acetylcholine receptor subunit alpha-type acr-7 status:Confirmed UniProt:P45963 protein_id:CAA85338.2 [WormBase]
  • gi|21264395|sp|P45963.2|ACR7_CAEEL RecName: Full=Acetylcholine receptor subunit alpha-type acr-7; Flags: Precursor [NCBI NR]
  • gi|17531181|ref|NP_495647.1| AcetylCholine Receptor family member (acr-7) [Caenorhabditis elegans] [NCBI NR]
  • gi|14530542|emb|CAA85338.2| C. elegans protein T09A5.3, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|11415007|gb|AAG35182.1| nicotinic acetylcholine receptor-like subunit ACR-7 [Caenorhabditis elegans] [NCBI NR]
  • Acetylcholine receptor subunit alpha-type acr-7 OS=Caenorhabditis elegans GN=acr-7 PE=1 SV=2 [Swiss-Prot]
  • (P45963) Acetylcholine receptor, alpha-type subunit acr-7 precursor [Swiss-Prot]
  • [wormpep67.fasta]
  • CE28078 WBGene00000046 locus:acr-7 Acetylcholine receptor status:Confirmed SW:P45963 protein_id:CAA85338.2 [wormpep150.fasta]
  • 28078 WBGene00000046 locus:acr-7 Acetylcholine receptor status:Confirmed SW:P45963 protein_id:CAA85338.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • acetylcholine receptor, one of nine alpha a7-like nicotinic acetylcholine receptor subunits (62.8 kD) (acr-7) [Caenorhabditis elegans]gi|14530542|emb|CAA85338.2| Hypothetical protein T09A5.3 [Caenorhabditis elegans]gi|11415007|gb|AAG35182.1| nicotinic a [nrdb_11152004_Chlamydomonas]
  • locus:acr-7 Acetylcholine receptor status:Confirmed SW:P45963 protein_id:CAA85338.2 [wormpep115.fasta.reversed]
  • CE28078 locus:acr-7 Acetylcholine receptor status:Confirmed SW:P45963 protein_id:CAA85338.2 [wormpep80.hongbin]
  • CE28078 WBGene00000046 locus:acr-7 Acetylcholine receptor status:Confirmed UniProt:P45963 protein_id:CAA85338.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE28078 WBGene00000046 locus:acr-7 Acetylcholine receptor status:Confirmed UniProt:P45963 protein_id:CAA85338.2| [wormORF-contam.fasta]
  • nicotinic acetylcholine receptor-like subunit ACR-7 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • AcetylCholine Receptor family member (acr-7) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein T09A5.3 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Acetylcholine receptor subunit alpha-type acr-7 precursor [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE28078 WBGene00000046 locus:acr-7 status:Confirmed UniProt:P45963 protein_id:CAA85338.2 Acetylcholine receptor subunit alpha-type acr-7 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 538 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: neurotransmitter receptor activity [IEALink to PubMed article]
    extracellular ligand-gated ion channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMVQSIQIVL PVALFFLIVF NGFTVEGSKK EAQLYRDLLT NYSYLVRPVR NPKKALTVTM  60
   61 KVFIQQVLLV DAKHQMIEVN AWLKYIWTDF RLRWNPLDYE NITSVRFQGE DQIWQPDILL 120
  121 YNRYIEDEQE SFDITYKTNA VAYSDGVINW IPPGIFKLSC KMDITLFPFD EQICFMKFGS 180
  181 WTYHGFALDL RLDVVKGQEP SADLSTYITN GEWHLLSAPA RREEKFYKCC KEPYPTVKFY 240
  241 LHLRRRTFYY VFNVVLPTLL VSFMSLLAFC LPATDLSEKI GLQTTILLSV CFFLTILSEM 300
  301 TPTTSEAVPL LGVFFSALTF IVAMSTTFTI LVLNIRYRQI TNHYLSPMFR SIFLECLPWL 360
  361 MMMKRPDHKF RRGSSYRDSS ADQCVQCAKN AELKSILRGT DNQQQIETNT FYPFPTETLS 420
  421 LNRKVGDGLF IQRRCQIHEE ARSEKFTHGM LACEKSLREN GSELANILVT ILKMYEVMVS 480
  481 QVERIRKRIA LKRKRKDIQD EWKFAAQAVD RFCLIIFTIV FIICCFIFVA IPPIKILD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..345] PSI-BLAST 76.045757 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    2 View Details [346..538] PSI-BLAST 39.0 Acetylcholine receptor protein, gamma chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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