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Protein Overview: lfe-2

General Information:
Name(s) found: lfe-2 / CE27862 [WormBase]
Description(s) found:
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  • WBGene00002979 locus:lfe-2 status:Confirmed UniProt:Q95Q62 protein_id:CCD66218.1 [WormBase]
  • gi|71981980|ref|NP_001021047.1| Let-23 Fertility effector/regulator family member (lfe-2) [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_491505.1| let-23 Fertility Effector/regulator LFE-2, 1D-myo-inositol-trisphosphate 3-kinase (56.8 kD) (lfe-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|14625143|gb|AAK71360.1|U88314_6 Let-23 fertility effector/regulator protein 2, isoform a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE27862 WBGene00002979 locus:lfe-2 status:Confirmed TR:Q95Q62 protein_id:AAK71360.1 [wormpep150.fasta]
  • 27862 WBGene00002979 locus:lfe-2 status:Confirmed TR:Q95Q62 protein_id:AAK71360.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • let-23 Fertility Effector/regulator LFE-2, 1D-myo-inositol-trisphosphate 3-kinase (56.8 kD) (lfe-2) [Caenorhabditis elegans]gi|14625143|gb|AAK71360.1| Let-23 fertility effector/regulator protein 2, isoform a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:lfe-2 status:Confirmed TR:Q95Q62 protein_id:AAK71360.1 [wormpep115.fasta.reversed]
  • CE27862 locus:lfe-2 status:Confirmed [wormpep80.hongbin]
  • CE27862 WBGene00002979 locus:lfe-2 status:Confirmed UniProt:Q95Q62_CAEEL protein_id:AAK71360.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE27862 WBGene00002979 locus:lfe-2 status:Confirmed UniProt:Q95Q62_CAEEL protein_id:AAK71360.1| [wormORF-contam.fasta]
  • Let-23 Fertility effector/regulator family member (lfe-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Let-23 fertility effector/regulator protein 2, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE27862 WBGene00002979 locus:lfe-2 status:Confirmed UniProt:Q95Q62 protein_id:AAK71360.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE27862 WBGene00002979 locus:lfe-2 status:Confirmed UniProt:Q95Q62 protein_id:CCD66218.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Let-23 Fertility Effector/regulator OS=Caenorhabditis elegans GN=lfe-2 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 494 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: inositol trisphosphate 3-kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHTQPQSYQA PEQTHMRIEN RRIEAGKGGT NLLLIIESRV DTLSINLPTL YSLLFTTNIT  60
   61 ILMSAPQHRQ LRRAAHITKI ASIDLCSLEE EDHEDLVLEE SGHHPSDIQN EKPNRPPYST 120
  121 LIRKRSGKVF RFVRPKLADL WHSRYHEASF DLGRRLGIGR RTQSCCEDVC DEEVSVETMA 180
  181 ITALPMDVWL KERLKKWVQL SGHEGSIVPA TPHTLYKKQC ANCGEGRAYK NISKDPALDG 240
  241 FTPKYYDELE KNEEHFIEIE DLLQQFHDPT KTAIMDIKIG TRTFLESEVS NTKKRADLYE 300
  301 KMVAIDNDEP TEEERKCGAI TKLRYMQFRE RESSTAQLGF RIEAAKRLEG ALEKNFKKVR 360
  361 TVEDVTTTFM DFFGTQRSRV RQQLIERLKS MRKAIEHSSF FNSHEVVGSS ILIVFDTEKV 420
  421 GCWMIDFAKS SPVPNGRTLN HRTTWIPGNN EDGYLIGIDN LVKILEELPE YGEHPDDQLM 480
  481 VTEEVIARMK NTKS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..182] MSA 1.046965 View MSA. No confident structure predictions are available.
    2 View Details [183..494] PSI-BLAST 91.522879 Crystal Structure of the Catalytic and CaM-Binding domains of Inositol 1,4,5-Trisphosphate 3-Kinase B


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle