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View Structure Prediction Details

Protein: lfe-2
Organism: Caenorhabditis elegans
Length: 494 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lfe-2.

Description E-value Query
Range
Subject
Range
gi|2898158, gi|7... - pir||T42444 1D-myo-inositol-trisphosphate 3-kinase (EC 2.7.1.127) 1 - Caenorhabditis elegans, gi|289...
634.0 [0..1] [494..1]

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Predicted Domain #1
Region A:
Residues: [1-182]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHTQPQSYQA PEQTHMRIEN RRIEAGKGGT NLLLIIESRV DTLSINLPTL YSLLFTTNIT  60
   61 ILMSAPQHRQ LRRAAHITKI ASIDLCSLEE EDHEDLVLEE SGHHPSDIQN EKPNRPPYST 120
  121 LIRKRSGKVF RFVRPKLADL WHSRYHEASF DLGRRLGIGR RTQSCCEDVC DEEVSVETMA 180
  181 IT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [183-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALPMDVWLKE RLKKWVQLSG HEGSIVPATP HTLYKKQCAN CGEGRAYKNI SKDPALDGFT  60
   61 PKYYDELEKN EEHFIEIEDL LQQFHDPTKT AIMDIKIGTR TFLESEVSNT KKRADLYEKM 120
  121 VAIDNDEPTE EERKCGAITK LRYMQFRERE SSTAQLGFRI EAAKRLEGAL EKNFKKVRTV 180
  181 EDVTTTFMDF FGTQRSRVRQ QLIERLKSMR KAIEHSSFFN SHEVVGSSIL IVFDTEKVGC 240
  241 WMIDFAKSSP VPNGRTLNHR TTWIPGNNED GYLIGIDNLV KILEELPEYG EHPDDQLMVT 300
  301 EEVIARMKNT KS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.522879
Match: 2aqxA
Description: Crystal Structure of the Catalytic and CaM-Binding domains of Inositol 1,4,5-Trisphosphate 3-Kinase B
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle