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Protein Overview: smn-1

General Information:
Name(s) found: smn-1 / CE27843 [WormBase]
Description(s) found:
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  • WBGene00004887 locus:smn-1 status:Confirmed UniProt:G5EC16 protein_id:CAC42273.1 [WormBase]
  • gi|71981679|ref|NP_001021034.1| SMN (human Survival Motor Neuron gene) homolog family member (smn-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|6002908|gb|AAF00192.1|AF156887_1 survival motor neuron protein [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_492525.1| human Survival Motor Neuron gene homolog (22.9 kD) (smn-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|14530375|emb|CAC42273.1| C. elegans protein C41G7.1b, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE27843 WBGene00004887 locus:smn-1 Human muscular atrophy protein like status:Confirmed TR:Q9U758 protein_id:CAC42273.1 [wormpep150.fasta]
  • 27843 WBGene00004887 locus:smn-1 Human muscular atrophy protein like status:Confirmed TR:Q9U758 protein_id:CAC42273.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • human Survival Motor Neuron gene homolog (22.9 kD) (smn-1) [Caenorhabditis elegans]gi|14530375|emb|CAC42273.1| Hypothetical protein C41G7.1b [Caenorhabditis elegans]gi|6002908|gb|AAF00192.1| survival motor neuron protein [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:smn-1 Human muscular atrophy protein like status:Confirmed TR:Q9U758 protein_id:CAC42273.1 [wormpep115.fasta.reversed]
  • CE27843 Human muscular atrophy protein like status:Confirmed TR:Q9U758 protein_id:CAC42273.1 [wormpep80.hongbin]
  • CE27843 WBGene00004887 locus:smn-1 Human muscular atrophy protein like status:Confirmed UniProt:Q9U758_CAEEL protein_id:CAC42273.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE27843 WBGene00004887 locus:smn-1 Human muscular atrophy protein like status:Confirmed UniProt:Q9U758_CAEEL protein_id:CAC42273.1| [wormORF-contam.fasta]
  • SMN (human Survival Motor Neuron gene) homolog family member (smn-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C41G7.1b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • survival motor neuron protein [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE27843 WBGene00004887 locus:smn-1 Human muscular atrophy protein like status:Confirmed UniProt:Q9U758 protein_id:CAC42273.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE27843 WBGene00004887 locus:smn-1 Human muscular atrophy protein like status:Confirmed UniProt:G5EC16 protein_id:CAC42273.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE27843 WBGene00004887 locus:smn-1 status:Confirmed UniProt:G5EC16 protein_id:CAC42273.1 [wormpep246-ecoli-contam.fasta]
  • SMN (Human Survival Motor Neuron gene) homolog OS=Caenorhabditis elegans GN=smn-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 207 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    cytoplasm [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed articleLink to PubMed article]
    mRNA processing [IEALink to PubMed article]
    spliceosome assembly [IEALink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKIWSKSGD MEVDDVWDDT ELIKMYDESL QEISKNETSA KITSRKFKGE DGKMYTWKVG  60
   61 GKCMAPYEEN GEVTDYPATI DTIGGADNLE VGVTFIYYGG QAVVQMKDLW LNEEAIADAV 120
  121 KAENDLQKTK KTSTVNSVAH SNSKSTSSAP NTSMPFPSFA PPVPPNIIAM APVNQKEAMN 180
  181 SMLMSWYMSG YHTGYYQALA DQKNVQN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] PSI-BLAST 24.221849 Survival motor neuron protein 1, smn
    2 View Details [139..207] MSA 1.028993 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.50121748882076 bayes_pls_golite062009
  • protein binding
    		•  0.95084028886111 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle