Protein Overview: sma-1

General Information:
Name(s) found:	sma-1 / CE27773 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00004855 locus:sma-1 status:Confirmed UniProt:G5EC35 protein_id:CAR64676.1 [WormBase] gi\|2997690\|gb\|AAC08577.1\| beta chain spectrin homolog Sma1 [Caenorhabditis elegans] [NCBI NR] gi\|25155104\|ref\|NP_741632.1\| SMAll family member (sma-1) [Caenorhabditis elegans] [NCBI NR] gi\|212646510\|ref\|NP_001129903.1\| SMAll family member (sma-1) [Caenorhabditis elegans] [NCBI NR] gi\|198447242\|emb\|CAR64676.1\| C. elegans protein R31.1b, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|198446549\|emb\|CAR64670.1\| C. elegans protein R31.1b, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|14530529\|emb\|CAB00130.2\| Hypothetical protein R31.1 [Caenorhabditis elegans] [NCBI NR] gi\|14530518\|emb\|CAB04608.2\| Hypothetical protein R31.1 [Caenorhabditis elegans] [NCBI NR] pir\|\|T42993 probable spectrin beta chain - Caenorhabditis elegans [NCBI NR] [wormpep67.fasta] CE27773 WBGene00004855 locus:sma-1 spectrin beta chain status:Confirmed TR:O02425 protein_id:CAB00130.2 [wormpep150.fasta] 27773 WBGene00004855 locus:sma-1 spectrin beta chain status:Partially_confirmed TR:O02425 protein_id:CAB00130.2 [wormpep130-phg-ecoli-orf-rand.fasta] SMAll body size SMA-1, betaH chain spectrin homolog required for embryonic elongation and morphogenesis; expressed in epithelial cells (470.0 kD) (sma-1) [Caenorhabditis elegans]gi\|14530518\|emb\|CAB04608.2\| Hypothetical protein R31.1 [Caenorhabditis elega [nrdb_11152004_Chlamydomonas] 27773 WBGene00004855 locus:sma-1 spectrin beta chain status:Confirmed TR:O02425 protein_id:CAB00130.2 [wormpep150-phg-orf-ecoli-rand.fasta] locus:sma-1 spectrin beta chain status:Partially_confirmed TR:O02425 protein_id:CAB00130.2 [wormpep115.fasta.reversed] CE27773 locus:sma-1 spectrin beta chain status:Partially_confirmed TR:O02425 protein_id:CAB00130.2 [wormpep80.hongbin] Hypothetical protein R31.1 [Caenorhabditis elegans] [nr-271106-contam.fasta] beta chain spectrin homolog Sma1 [Caenorhabditis elegans] [nr-271106-contam.fasta] SMAll family member (sma-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE27773 WBGene00004855 locus:sma-1 spectrin beta chain status:Partially_confirmed TR:O02425 protein_id:CAB00130.2 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta] CE27773 WBGene00004855 locus:sma-1 status:Confirmed UniProt:Q7KPM2 protein_id:CAR64676.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE27773 WBGene00004855 locus:sma-1 status:Confirmed UniProt:Q7KPM2_CAEEL protein_id:CAR64676.1 [wormbase_c-elegans_197_11-26-2008_reversed.fasta] CE27773 WBGene00004855 locus:sma-1 status:Confirmed UniProt:G5EC35 protein_id:CAR64676.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] Isoform of G5EFW3, Beta chain spectrin homolog Sma1 OS=Caenorhabditis elegans GN=sma-1 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	4063 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA] apical plasma membrane [IDA] proteinaceous extracellular matrix [IEA]
Biological Process:	DNA repair [IEA] collagen and cuticulin-based cuticle development [IMP ] regulation of locomotion [IGI][IMP] embryonic body morphogenesis [IMP] positive regulation of growth rate [IMP ] post-embryonic body morphogenesis [IMP] body morphogenesis [IMP] positive regulation of organ growth [IMP] cell adhesion [IEA] blood coagulation [IEA] positive regulation of multicellular organism growth [IMP ] locomotory behavior [IMP] positive regulation of cell size [IMP] nematode larval development [IGI] oviposition [IMP]
Molecular Function:	actin binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKYEMQVRV PTSGAPPVRA DANGTDQDEF NNETLYFERS RIRTLQDERV HIQKKTFTKW  60
   61 CNSFLNRASL EIVDLFEDVG DGIMLMKLLE IISGDKLGKP NRGRMRVQKV ENLNKVLDFL 120
  121 KKKKIQLENI GAEDILDRNE RLILGLIWTI ILRFQIDTIV IEDEEERGER KHAKDALLLW 180
  181 CQRKTAGYPN VRIENFTTSW RNGLAFNALI HSHRPDLVDF NRLNPNEHVD NLNHAFDVAE 240
  241 KKLEIARLLD AEDVDVTRPD EKSIITYVSL YYHHFAKQKT EMTGARRIAN IVGKLMVSET 300
  301 MEDDYEHIAS ELLNWIRVTI KTLESRRFPN SLNGMREEHA KFNQFRTSEK PPKYKEKGEL 360
  361 EALFFTIQTK RKAMSRKQYQ PPQGLFMHDI ESAWAQLDYA ENERQVAIIA ELQRQEKLEQ 420
  421 LAQRFHKKAK LRDSWLRSVQ VVLEEMEHGR SASQVEKTLK KQQAISTDIL AREDRFKMLT 480
  481 AMCNELCTEK YHESDKVRGM EREIIDRWTQ LLTLLEQRKR ALMSLNDLMS LLRDIDTLSN 540
  541 ELYSLEPAVR NRDVGKHLIG VEDLLGKHDL LDAQINAHGS LLSKLSQSAN NYIRHKEEQF 600
  601 DVLQRKLDEV TAQYNTLVEL CRSRRLGLER ARSLFQFVQD HEEEMAWLAE KEKLCTTALN 660
  661 SGDISAVPQT TLLYKNVEME MQTHWARSKG MIAGGERLVQ NGQSKEDIQR RLTQMNHRWE 720
  721 RLRVAVDALG NWLSEARHAQ QYFQDANEAE SWIREKMPLV KSDDLGRDEG AAESLLQRHA 780
  781 RLEEEIRAYK SDISRLEEMQ SQLANSAFHT ATTSQSVQET EEVNVPQVEM SYNYEGNGMR 840
  841 VSKGEVLALL EKSTPEWWRA LKRDGTEGYV PANYCKIVPG ETVTVTQTTQ KTTTTLEGNE 900
  901 TKSSVVADRQ HKISNDYREL KRLADVRRRL LSDNIKLLRF YRECDEFERW AKEIEVSLAD 960
  961 EPSPEHVAAF RRKFDKLEAD MKTNGGTQLK HINDIANDLI SEGHGQSRKI EVRQHKINAM1020
 1021 WDNLERLRKQ RGVRLEATER VADFDTTCES AREWMLSKFE QLDRNPNDVK SLQNLERDLK1080
 1081 PLEDKIAALE KLAAAVKKDH PEEAAAIERK IAELRALHAD LLRRAQEKML LAEQTQGKEM1140
 1141 FESALRDMIG WIEKTRKVMM EDVHPVDVAE AEELLKKHYE LGEQIKDKKY EVEYCQELGR1200
 1201 RLLERNPRMS KVEEQLQNLV SEMASLRDLY RRRDTILKQQ LDLQLFNRES ERIDAATKGH1260
 1261 EAFLEFDNLG DSVESVENLL KRHRDLEAKL DAQEARLEAF SRTADDMIKA QHADSAYIEQ1320
 1321 RRRDVLARRE AVRRAAAQRK KQLEASLEYQ EMRREADEVV GWMYEKAKLV MSGDDSALAP1380
 1381 SAIPHRLLKH EAFEAEIIAN EPRIQQINSE GDGLVSKKHY ESPNVEKIVR QVNAQWGDLK1440
 1441 KQVWNKGLRL RQAADQKGLD RILEDAHAKL DEMQTALNSK DQGLDLRSVK DLLQKHAVLE1500
 1501 QEMGLYGNKL SDIENRGKKM AVDGHYDADR IHSTVGQLLQ RYAAMKGPAQ RRKGDLDESR1560
 1561 LWHQLVFDVD CELQWIAEKK PIASSQDCGR TLTEALNMVK KQEQLEAEVN QHGGQIDKVL1620
 1621 LQAGELIKRH HSASSQIKAK SSELETAWSE LKKLLRLRRA VVDWGVKEQQ YLFDAAEVES1680
 1681 WMNEKRNALA SEDYGNDEDA ARKLLSKHRA LCEDMTTYRQ WLEKLEVKCV ELVESNRPHV1740
 1741 ERFQKRQDEL VREFDALSKL AEDRRNALED AVCLYEYMRE SADLGQSIEE NLRVAMSEEF1800
 1801 AEDYEHLKEL QSKFDEFKQK VKNGSERFTS CETAANAILR RNPPFARDVV KKQEALRTAW1860
 1861 NTLCEYIEAR DSKLAVAEEL HRFHRDVDEF EQWMADKMAN MPRDLGRDVK HVHSLWQHHE1920
 1921 ALDKEIHNSQ PRLAKLVEEA ERLKKTYPGG NAEQIGGRQQ TLEQEWEELK NATDDRKDML1980
 1981 RAAFDLHTFN GKVRDLLAWT DLTISDIQSD LHINDLQQAE WLQTEHSRLS HEMDAREPEF2040
 2041 ARLVNDGEKM ITAQHYASEE IKNKTHLLKS ALERLRSEWA LRNGFLSQAV QWHAFQREAK2100
 2101 QIIASIGSKR TTLRSLAVGG SVADVESQTK RLDTFEKALS TLDERTATLD HTANELMKAR2160
 2161 HMESKNISMW QSNVHEELKL LRQDIEARHA MLKDAFALAS FDSDVAQIEA WIDEKTNGVR2220
 2221 KAQDLSSESI SIDEKMKRLQ THQALEAEVT ANKPVVDQIL QRGNQLKNLH RNPKIANRCD2280
 2281 ELSYKWNQLS GACADQSLAL EEARDLLRFK QLVENVLAWI NEKEVLVSTA DMGKDMEHCR2340
 2341 LLLERLDGTR SDSIVDEQTL DEINRLGEKL VKQGRSSRDQ VQKEQQHLNE KWRLLLGQLA2400
 2401 HYRTELLAAM EVHTFNRDVE DTDERIHEKV AAMKSDDYGK DFASVELLVR KQSALERDMS2460
 2461 AIHQKLIAHD KDAQKILEKR PPLRETVLDS LKKLEESWEQ LSKAAELRNE KLNRSFKLYK2520
 2521 YLDDVKKVEQ WANQVRNKMT SHQTPKDSNG ARKILEQHHE RKAEIDGRSE ELRLLHEEGQ2580
 2581 ALNQEQPEHK AEVQRAHKRV QNSEHQLRQT WESEKGTLQK LLEWMLWCDE AVQCEQWLSD2640
 2641 KETQVARGEL GDTTDAVEML IKGHSAFEET VRKQSEKIDA LTKNADALVS GGNNYRADIV2700
 2701 TRSEEVTARH ALLLKSMEKR GHMLEDSKKY HEFIRQCGEL IIWITAKLQL AYDESFLDHT2760
 2761 NLRSKLQKHM AFDSELVENE KRLSTVERQG EQLVTDNHFM SEQVKAQLVE LRSGWDELRT2820
 2821 KSALKTQRLR EAFELHSLQR KVEDIEKWLD KVEGELSSDD HGRDILSTEL LIKKLDTLQT2880
 2881 EIAGRSDAVV EMMKKARELR VQGSAAADDC LKQAEQVEAR YSGLDEPVQI RRENLVDAQA2940
 2941 FFQWVKAAEE DLEWLSDRMM LASSGESGDS LQSALSLQKK HATLEKELDT RQSAMNDTEQ3000
 3001 RGKDMIRQRH FASTHIQKIL DRLSSAMLTL KESCGLRRDL LQEAIDAHEY YTEETEAEQW3060
 3061 LREQMPLAMS QEMGRDQAGA ESHLRRLTVL DKEVELFKNE IDRLKKRADG LLAREHHDAM3120
 3121 SIAAKQRKLE ALFGDLCREC ARRRTQIVDA SKYHKFVRQA DDLSDWLREK ERSASAEDYG3180
 3181 QDLEDCQQII EQFESTVREL AAAGERVAAV QRAQEDLLRS GHPYGASITA KGADVQRLWT3240
 3241 HVNEVANERK QALNGARQVH RFDQEADQIL NWLQDKEATG VAMEQEDLSR ADLASVKAQL3300
 3301 QRHDEFMHGM KAVEKQVAEL CHEAERLWNS FPDTRHHLEV RRLDMEEQLK DILEAAKKHL3360
 3361 EKLRHMQSLQ SYFQEYREMM QWMKNMQSTM TSEQLPRDVA SCESLVRRHD EYNLEMQGRK3420
 3421 PFVDDFARQG RRMIQSSHVL SQEIQEKVDI LEKSWAMLCE IWKDRAELYE ENMDVQKWKQ3480
 3481 NAEQLDSWLE ERAGLLGDDW RMVDSVEMAE THLRDFDDFL VTLEAQSEKC DMVKRLTLVE3540
 3541 QNFSRLRSKE IDRARIAEDD QKRRDTIKIV EKGNILANRR QERERRKTQE ISLLRPSPSG3600
 3601 EEFSTHTMPR KERKDRAKTT ADLAPGAIQI GDILASSSTV APLQSGVEMT KTPSFNTRRT3660
 3661 QSIRKGSRWE DMGAIDMKGF FDRKQCQQSG GKRATIRSWK NYYGILCGQL LCFFKDEQQF3720
 3721 LENVAAAPPV YIYGAQCEQY PEYAKRKNSF RLLLQDGSEF IFSCPDERQM LEWVAKIKFH3780
 3781 AHLTPSNQLK SYAYNDDLFQ SPDQPPMVAP RRNIGGHDVA NRMSHASSVF TTSDDLEQHE3840
 3841 LDYSRRCSSL PRGKHSGQIT MRDCATLPRG FGSDVMEQQP TAFFPPSGPL LATPSVLTMS3900
 3901 SSSMTANVMP TVVTRKIGVV RRASRRQSVY AESIYGEVEQ AIAEANRVST SRPNGDHAEL3960
 3961 RHTIQVHPGS SGYTETLMYK EHTSSNYQPM ERSVSPRNQQ NGEFITWVES NQQNQPMNTP4020
 4021 DGRSTSASVV STPSNYDDSD SIKSSSKRKG FGSLFKRGSK HSK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.86

Protein Overview: sma-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: