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Protein Overview: sptl-2

General Information:
Name(s) found: sptl-2 / CE27380 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00018398 locus:sptl-2 Serine palmitoyltransferase 2 status:Confirmed UniProt:Q20375 protein_id:CCD71174.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 586 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEALink to PubMed article]
    tetrapyrrole biosynthetic process [IEALink to PubMed article]
    biotin biosynthetic process [IEALink to PubMed article]
    biosynthetic process [IEALink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEALink to PubMed article]
    transferase activity, transferring nitrogenous groups [IEALink to PubMed article]
    glycine C-acetyltransferase activity [IEALink to PubMed article]
    transferase activity [IEALink to PubMed article]
    5-aminolevulinate synthase activity [IEALink to PubMed article]
    8-amino-7-oxononanoate synthase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSEVAKRNS PFRFLHKLPI RLTFTEKKSP LLISDLAKQR EENDELKKRT HILECAWNQE  60
   61 HDDDEEEEEV KVDQGSEETT SSHDIYGDVG KRAPNEFEKI DRLTTIKVYI AWLALFVFAH 120
  121 IREYVTRFGF VKDLSSKENA KMKDFVPLFS DFEAFYQRNC YIKVRDVFER PICSVPGATV 180
  181 DLVDRVSHDG NWTYEYPGTR TNVINVGSYN YLGFAQSAGP CAEQSASSID REGLSCCTTV 240
  241 HERGRSVSQA KLEKLVAEFL GVEDAICFSM GFATNSMNAP CLVDKHSLII SDKYNHASLI 300
  301 LGCRLSGAST KVFEHNDMES LERILRDAIA YGNPKTHRPY KKILIIVEGI YSMEGSICNL 360
  361 PGIIALKKKY QAYLYLDEAH SIGAMGKTGK GVVEYWGCDP KDVDILMGTF TKSFGAAGGY 420
  421 IAGSKRTVDH LRAASPTGYY SSPMSPPIAQ QIYTSMSIIM GKDGTKDGAQ RIERLARNSH 480
  481 YFRMKLKQNG FIVYGSNDSP VVPMLIYFPT MCGFYGREML ARNIGCVVVS FPATHMTEGR 540
  541 VRFCISAAHT KEQLDEVLET VNLLGSMSRS KFSKRSHLYK NQKIEW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] deduced N/A No confident structure predictions are available.
    2 View Details [172..586] PSI-BLAST 87.522879 2-amino-3-ketobutyrate CoA ligase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • serine C-palmitoyltransferase activity
    		•  9.1839236553858 bayes_pls_golite062009
  • C-palmitoyltransferase activity
    		•  9.1839236553858 bayes_pls_golite062009
  • C-acyltransferase activity
    		•  4.29379571948906 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  3.15163480353521 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  2.82458180884712 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • N-succinyltransferase activity
    		•  1.81799375593294 bayes_pls_golite062009
  • threonine aldolase activity
    		•  1.80396420390785 bayes_pls_golite062009
  • adenosylmethionine-8-amino-7-oxononanoate transaminase activity
    		•  1.74778109525713 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.46601963907552 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.46601963907552 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.07873942461292 bayes_pls_golite062009
  • glycine C-acetyltransferase activity
    		•  0.935794708043259 bayes_pls_golite062009
  • DNA binding
    		•  0.886628214497634 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.814403324199462 bayes_pls_golite062009
  • structural molecule activity
    		•  0.811208803619077 bayes_pls_golite062009
  • transferase activity
    		•  0.737426388870721 bayes_pls_golite062009
  • carbon-sulfur lyase activity
    		•  0.698312655247044 bayes_pls_golite062009
  • binding
    		•  0.661198018681765 bayes_pls_golite062009
  • intramolecular transferase activity, transferring amino groups
    		•  0.659071155545801 bayes_pls_golite062009
  • transcription factor activity
    		•  0.615294010373048 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.319452731970428 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.15938456446406 bayes_pls_golite062009
  • sulfurtransferase activity
    		•  0.0450490929307473 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

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    Created and Maintained by: Michael Riffle