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Protein Overview: wrm-1

General Information:
Name(s) found: wrm-1 / CE26743 [WormBase]
Description(s) found:
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  • WBGene00006943 locus:wrm-1 Armadillo repeat-containing protein wrm-1 status:Confirmed UniProt:Q10953 protein_id:CCD61515.1 [WormBase]
  • pir||T03746 hypothetical protein wrm-1 - Caenorhabditis elegans [NCBI NR]
  • gi|74962076|sp|Q10953.2|WRM1_CAEEL RecName: Full=Armadillo repeat-containing protein wrm-1; AltName: Full=Worm armadillo protein 1 [NCBI NR]
  • gi|2343265|gb|AAC47748.1| wrm-1 gene product [Caenorhabditis elegans] [NCBI NR]
  • gi|17555542|ref|NP_498236.1| Worm aRMadillo family member (wrm-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|13324878|gb|AAK18863.1| Worm armadillo protein 1 [Caenorhabditis elegans] [NCBI NR]
  • Armadillo repeat-containing protein wrm-1 OS=Caenorhabditis elegans GN=wrm-1 PE=1 SV=2 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE26743 WBGene00006943 locus:wrm-1 status:Confirmed TR:Q10953 protein_id:AAK18863.1 [wormpep150.fasta]
  • 26743 WBGene00006943 locus:wrm-1 status:Partially_confirmed TR:Q10953 protein_id:AAK18863.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • worm aRMadillo (90.3 kD) (wrm-1) [Caenorhabditis elegans]gi|13324878|gb|AAK18863.1| Worm armadillo protein 1 [Caenorhabditis elegans]gi|7509202|pir||T03746 hypothetical protein wrm-1 - Caenorhabditis elegansgi|2343265|gb|AAC47748.1| wrm-1 gene product [nrdb_11152004_Chlamydomonas]
  • CE26743 WBGene00006943 locus:wrm-1 status:Partially_confirmed TR:Q10953 protein_id:AAK18863.1 [wormpep132.fasta]
  • 26743 WBGene00006943 locus:wrm-1 status:Confirmed TR:Q10953 protein_id:AAK18863.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:wrm-1 status:Partially_confirmed TR:Q10953 protein_id:AAK18863.1 [wormpep115.fasta.reversed]
  • CE26743 locus:wrm-1 status:Partially_confirmed [wormpep80.hongbin]
  • CE26743 WBGene00006943 locus:wrm-1 status:Confirmed UniProt:WRM1_CAEEL protein_id:AAK18863.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE26743 WBGene00006943 locus:wrm-1 status:Confirmed UniProt:Q10953_CAEEL protein_id:AAK18863.1| [wormORF-contam.fasta]
  • Worm aRMadillo family member (wrm-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • wrm-1 gene product [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Worm armadillo protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE26743 WBGene00006943 locus:wrm-1 status:Confirmed UniProt:Q10953 protein_id:AAK18863.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE26743 WBGene00006943 locus:wrm-1 status:Confirmed UniProt:Q10953 protein_id:CCD61515.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE26743 WBGene00006943 locus:wrm-1 status:Confirmed UniProt:Q10953 protein_id:CCD61515.1 Armadillo repeat-containing protein wrm-1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 796 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cell cortex [IDA]
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    polarity specification of proximal/distal axis [IMPLink to PubMed article]
    spindle organization [IMPLink to PubMed article]
    asymmetric protein localization involved in cell fate determination [IMPLink to PubMed article]
    embryonic body morphogenesis [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    endodermal cell fate specification [IMPLink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IDALink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    transcription coactivator activity [IDALink to PubMed article]
    transcription factor binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVDCAETFS QPCTPLNFNP MTPSTSRVST PVRPSSTMSA RQYSGSPFKA QPQNMEPSNS  60
   61 RVQELREAAV GKRSYTNAWM QGTYAPPQMA GQQQRFSRPP SVIGSTMSHM TNMSEMTAYS 120
  121 YGGLSMLSVN TEMGEFNNFV NQAPYQRALT RVSQVSENQD PTNRQYPMTA PEIIENLEST 180
  181 ELINQAAAIR ALEPIVKAGG MLQTWGPKGA EPIIRALFQV LIPRPVENEN VIRKAFEILH 240
  241 HSILLSNKEI RRIDRMFFRL NAALMDPNGP PVFNVPKPYS IYEIVMTRAI QLDTKFESSA 300
  301 MVLLVHLCCK PHFMKIFFGE DETQQSPAHR RLHKIVIEFA IGNLRRPETK SKNKGLCVSI 360
  361 IKNLSNKNAT IKDMSERLGV VSLFHQIMQN EVIHEDLLWS TMQALTVFCG DVKNGTHFVQ 420
  421 MGGAQVLCGL LSHGSTRLLH ELLKCLRRVS DLPAIQEQDM KESIHCIVQL IGCSDVTIVE 480
  481 LATGTLRNIG LHNKMNKAFM VQDGVTSHAI AVLRTSEQFT YQPHANIDLY RKQILSIYEN 540
  541 CLSVLNNVTS MAPQDIKESA VSACRMISEN ADSAYVLLHY FNVGNRKCRK LAVTVMKRVI 600
  601 ETVPAFADPF VDLLGTTNEP LPILLLQRAF QSLDEWRKTS VEMMNCDGRS AEQRRELDDR 660
  661 RKDHEDIVKR SVGLLTNLCS QANPRFFHSL KLVLTNGTLN PFQWLTHEMS DGILQEWLAF 720
  721 ILSICSRDES LQTFMMYRFL EQAKMTEAFF AELKARRQNS NIQTMLSKII DLGRHQQRIV 780
  781 SQQHQQHQMQ HHRQLM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..111] deduced N/A No confident structure predictions are available.
    2 View Details [112..208] PSI-BLAST 83.0 Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
    3 View Details [209..796] PSI-BLAST 89.09691 beta-Catenin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.5792930989505 bayes_pls_golite062009
  • protein transporter activity
    		•  1.46178231098581 bayes_pls_golite062009
  • protein binding
    		•  1.041337870941 bayes_pls_golite062009
  • transporter activity
    		•  0.53053318170156 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.11990405994399 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle